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  • © 1982

Methods in Protein Sequence Analysis

Part of the book series: Experimental Biology and Medicine (EBAM, volume 3)

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eBook USD 149.00
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  • ISBN: 978-1-4612-5832-2
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Softcover Book USD 189.00
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Table of contents (69 chapters)

  1. Solid Phase Sequencing

    1. The use of Dabitc in Automated Solid-Phase Sequencing

      • Johann Salnikow, Arnold Lehmann, Brigitte Wittmann-Liebold
      Pages 181-188
    2. Improved Automatic Conversion for Use with a Liquid-Phase Sequenator

      • Michael N. Margolies, Andrew Brauer, Christine Oman, David G. Klapper, Marcus J. Horn
      Pages 189-203
    3. A Study of the Edman Degradation in the Assessment of the Purity of Synthetic Peptides

      • Stephen B. H. Kent, Mark Riemen, Marie LeDoux, R. B. Merrifield
      Pages 205-213
    4. Solid Phase Synthesis of Polypeptides and Oligonucleotides Using a Solid Phase Sequencer

      • Alex G. Bonner, Marcus J. Horn, Richard S. Neves, Stephen B. H. Kent
      Pages 215-219
  2. Manual Sequencing

    1. Front Matter

      Pages 221-221
    2. Manual Batchwise Sequencing Methods

      • George E. Tarr
      Pages 223-232
    3. Micro Quantitative Edman Manual Sequencing

      • Clyde Zalut
      Pages 233-239
  3. Sequencing by Mass Spectrometry

    1. Front Matter

      Pages 241-241
    2. Protein Sequencing by Mass Spectrometry

      • H. R. Morris, G. W. Taylor, M. Panico, A. Dell, A. T. Etienne, R. A. McDowell et al.
      Pages 243-261
  4. Cleavage of Proteins

    1. Front Matter

      Pages 289-289
    2. Enzymic Cleavage of Proteins

      • B. Keil
      Pages 291-304
    3. Chemical Cleavage of Proteins

      • Mark A. Hermodson
      Pages 313-323
    4. Protein Fragmentation with o-Iodosobenzoic Acid

      • A. Fontana, D. Dalzoppo, C. Grandi, M. Zambonin
      Pages 325-334
  5. Coordination of Protein and DNA Sequencing

    1. Front Matter

      Pages 335-335
    2. Analysis of the Escherichia Coli ATP-Synthase Complex by DNA and Protein Sequencing

      • John E. Walker, Alex Eberle, Nicholas J. Gay, Peter Hanisch, Matti Saraste, Michael J. Runswick
      Pages 337-354

About this book

Methods in Protein Sequence Analysis contains an intensely prac­ tical account of all the new methodology available to scientists carrying out protein and peptide sequencing studies. Many of the striking advances in fields as diverse as immunology, cell motility, and neurochemistry have in fact been fueled by our ever more powerful ability to determine the sequences and structures of key proteins and peptides. It is our hope that the rich array of tech­ niques and methods for sequencing proteins discussed in this volume-methods that generate much of the information crucial to progress in modern biology-will now become accessible to all who can benefit from them. The papers of the present volume constitute the Proceedings of the IVth International Conference on Methods in Protein Se­ quence Analysis, which was held at Brookhaven National Labo­ ratory, Upton, NY, September 21-25, 1981. It was the most recent in a series of biennial conferences, the previous one having been held in Heidelberg, GFR, in 1979. The series was originated by Richard Laursen, and initially dealt with one aspect of the field, solid-phase sequencing. The scope of the meeting was very broad and among the many aspects of protein sequencing discussed were: instrumentation, strategy, chemicals, mass spectrometry, cleavage of proteins and separation of peptides, and solid, liquid, manual, and even "gas­ phase" sequencing.

Keywords

  • ATP
  • ATP-Synthase
  • Amino acid
  • DNA
  • Methodologie
  • Nucleotide
  • RNA
  • enzymes
  • primary structure
  • protein sequence
  • protein structure
  • proteins

Editors and Affiliations

  • Brookhaven National Laboratory, Upton, USA

    Marshall Elzinga

Bibliographic Information

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • ISBN: 978-1-4612-5832-2
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 189.00
Price excludes VAT (USA)
Hardcover Book USD 299.00
Price excludes VAT (USA)