Overview
- Outlines indications for use of IgG concentrates and other modern immunomodulators
- Reviews basic aspects of IgG concentrates
- Provides an update on immunomodulatory IgG treatment in ITP
- Examines mAbs as immunomodulators and anticancer agents
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Table of contents (21 chapters)
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Update of Substitutive and Immunomodulatory Antibodies/Drugs Indications
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Immune Thrombocytopenia: The First Immunomodulatory IgG Treatment
Keywords
About this book
Reviews
“The book strives to provide basic information on current immunomodulation primarily covering clinical aspects with a few preclinical studies. … Overall, this is an excellent book on the subject that is delivered in a practical manual format.” (Ravi Salgia, Doody's Book Reviews, March, 22 , 2019)
Editors and Affiliations
About the editor
Paul (August) Imbach is a highly respected pediatric oncologist-hematologist who has developed worldwide clinical research on the indications for intravenous immunoglobulin. Dr. Imbach graduated in Medicine in 1972. He went on to structure the Swiss Pediatric Oncology Group (SPOG) and in 1978 performed the first autologous stem cell transplantation in Switzerland. He discovered the immunomodulatory effects of human immunoglobulin G concentrate (IVIG) in childhood immune thrombocytopenia (as reported in Lancet in 1981). In 1990, Dr. Imbach began working at the University Children’s Hospital Basel, where he started stem cell transplantation in children and was appointed Head of Pediatric Oncology-Hematology. He was subsequently elected as full professor and also as Dean of Education introducing a thorough curriculum reform of the medical faculty at the University of Basel. In parallel to his other activities, he co-founded the International Cooperative ITP Study ICIS group, which nowhas more than 90 centers worldwide. He has served as president of medical societies and foundations, is a member of various medical editorial boards, and has published over 300 peer-reviewed articles as well as the textbook Pediatric Oncology – A Comprehensive Guide (3rd edition 2014) in German and English. In 2015 he was awarded the Guido Fanconi Prize, the highest award of the Swiss Society of Pediatrics.
Bibliographic Information
Book Title: Antibody Therapy
Book Subtitle: Substitution – Immunomodulation – Monoclonal Immunotherapy
Editors: Paul Imbach
DOI: https://doi.org/10.1007/978-3-319-68038-5
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-68037-8Published: 10 April 2018
Softcover ISBN: 978-3-030-09819-3Published: 08 January 2019
eBook ISBN: 978-3-319-68038-5Published: 29 March 2018
Edition Number: 1
Number of Pages: XIV, 363
Number of Illustrations: 15 b/w illustrations, 32 illustrations in colour
Topics: Hematology, Immunology, Oncology