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Table of contents (28 protocols)
About this book
Reviews
"The introductory chapter by the editors gives a beautifully brief and concise overview of the entire family of DNA topoisomerases and related enzymes and can be used as an Ariadne's thread to the key papers of the field. Another useful item is the appended compendium of topoisomerase sequences, which is likely to be helpful in designing expression vectors, deletion mutants, etc. Most of the other chapters contain a lot of useful information and easily followed procedures.a very valuable addition to the topoisomerase literature. It summarizes a lot of useful information for those engaged or getting engaged in research on DNA topology or topoisomerases. Those just wanting to carry out some of the analytical procedures will in most cases find what they need, i.e. a concise delineation of the analytical background, some detailed and easy to follow protocols, and a comprehensive guideline for the interpretation of the results. As such, the book definitely deserves a place on many laboratory shelves"-FEBS Letters
"The introductory chapter is one of the most concise and clearly presented summaries of our current knowledge that has been written, and it will be useful even for experts in the field....The volume concludes with a well-organized and useful compendium of toposomerase DNA sequences. Volume I is clearly a valuable source of methodological expertise for anyone studying topoisomerases."-New Biological Books
"...We recommend greatly this remarkable book to all our readers, without exception." - Cellular and Molecular Biology
Editors and Affiliations
Bibliographic Information
Book Title: DNA Topoisomerase Protocols
Book Subtitle: Volume I: DNA Topology and Enzymes
Editors: Mary-Ann Bjornsti, Neil Osheroff
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1385/1592592597
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 1999
Hardcover ISBN: 978-0-89603-444-0Published: 23 March 1999
Softcover ISBN: 978-1-61737-039-7Published: 10 November 2010
eBook ISBN: 978-1-59259-259-3Published: 03 February 2008
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 327
Topics: Cell Biology
Industry Sectors: Biotechnology, Pharma