Overview
- Editors:
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Marc Bygdeman
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Department of Obstetrics and Gynecology, Karolinska Hospital, 01 Stockholm, Sweden
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Gary S. Berger
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Chapel Hill Fertility Services, Chapel Hill, USA
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Louis G. Keith
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Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, USA
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Table of contents (19 chapters)
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Basic Science
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- F. A. Kimball, K. T. Kirton
Pages 3-12
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Reproductive Physiology
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- L. Hamberger, P. O. Janson, L. Nilsson
Pages 99-108
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Clinical Applications
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Front Matter
Pages 143-143
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- S. S. Ratnam, R. N. V. Prasad
Pages 253-270
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- P. T. Russell, O. M. Owens
Pages 315-334
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Future Applications
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Front Matter
Pages 335-335
About this book
It is clear today that several prostaglandins play an important role in the regulation of many of the physiological events of the reproductive organs in the human. Both naturally occurring prostaglandins and their analogues are used routinely in many countries to ripen the cervix and induce labour at term as well as to dilate the cervix and to terminate pregnancy. Prostaglandin biosynthesis inhibitors are widely used in the treatment of primary dysmenorrhoea. The editors have aimed at an accurate, thorough, yet easily under standable review of the status in 1986 of medical knowledge regarding both the physiological importance and the clinical use of prostaglan dins and their inhibitors in obstetrics and gynaecology. I believe this book will be of value for all clinicians concerned with reproductive health. The list of authors guarantees an authoritative and up-to-date review of this active field. SUNE BERGSTROM Karolinska Institutet, Stockholm, Sweden Table Examples of clinical use of natural prostaglandins and some prostaglandin analogues Indications Prostaglandin Route of administration Manufacturer Dilatation of the cervix prior 15-methyl-PGF • Intramuscular Upjohn, USA 2 to vacuum aspiration 16-phenoxy-PGE methyl sulphonylamide Intramuscular Schering AG, West Germany 2 16,16-dimethyl-PGE methyl ester 1 Vaginal ONO, Japan; May & Baker, UK Second trimester abortion Intra -amniotic Upjohn, USA; ONO, Japan PGF 20 Upjohn, USA PGE Vaginal 2 Upjohn, USA 15-methyl-PGF 2.
Editors and Affiliations
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Department of Obstetrics and Gynecology, Karolinska Hospital, 01 Stockholm, Sweden
Marc Bygdeman
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Chapel Hill Fertility Services, Chapel Hill, USA
Gary S. Berger
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Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, USA
Louis G. Keith