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Multiple System Atrophy

  • Gregor K. Wenning
  • Alessandra Fanciulli

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Alessandra Fanciulli, Gregor K. Wenning
    Pages 1-9
  3. Florian Krismer, Gregor K. Wenning
    Pages 11-15
  4. Kurt Jellinger
    Pages 17-56
  5. Kurt Jellinger, Florian Krismer
    Pages 57-81
  6. Nadia Stefanova
    Pages 83-96
  7. Alessandra Fanciulli, Gregor K. Wenning
    Pages 97-119
  8. Alessandra Fanciulli, Gregor K. Wenning
    Pages 121-132
  9. Alessandra Fanciulli, Gregor K. Wenning
    Pages 133-142
  10. Florian Krismer, Gregor K. Wenning
    Pages 143-168
  11. Alessandra Fanciulli, Gregor K. Wenning
    Pages 169-194
  12. Back Matter
    Pages 195-198

About this book

Introduction

This textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson`s disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders.

Keywords

Alpha-synucleinopathies Movement Disorders Neurodegeneration Parkinson´s Disease Substantia Nigra

Editors and affiliations

  • Gregor K. Wenning
    • 1
  • Alessandra Fanciulli
    • 2
  1. 1.Division of Clinical NeurobiologyInnsbruck Medical UniversityInnsbruckAustria
  2. 2.Department of Neurology Division of NeurobiologyInnsbruck Medical UniversityInnsbruckAustria

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7091-0687-7
  • Copyright Information Springer-Verlag Wien 2014
  • Publisher Name Springer, Vienna
  • eBook Packages Medicine
  • Print ISBN 978-3-7091-0686-0
  • Online ISBN 978-3-7091-0687-7
  • Buy this book on publisher's site
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