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Principles of Peptide Synthesis

  • Book
  • © 1984

Overview

Authors:
  1. Miklos Bodanszky

    1. Department of Chemistry, Case Western Reserve University, Cleveland, USA

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Part of the book series: Reactivity and Structure: Concepts in Organic Chemistry (REACTIVITY, volume 16)

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Table of contents (8 chapters)

  1. Front Matter

    Pages I-XVI
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  2. Introduction

    • Miklos Bodanszky
    Pages 1-8

  3. Activation and Coupling

    • Miklos Bodanszky
    Pages 9-58

  4. Reversible Blocking of Amino and Carboxyl Groups

    • Miklos Bodanszky
    Pages 59-118

  5. Semipermanent Protection of Side Chain Functions

    • Miklos Bodanszky
    Pages 119-157

  6. Side Reactions in Peptide Synthesis

    • Miklos Bodanszky
    Pages 158-201

  7. Tactics and Strategy in Peptide Synthesis

    • Miklos Bodanszky
    Pages 202-232

  8. Techniques for the Facilitation of Peptide Synthesis

    • Miklos Bodanszky
    Pages 233-254

  9. Recent Developments and Perspectives

    • Miklos Bodanszky
    Pages 255-268

  10. Back Matter

    Pages 269-307
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Keywords

About this book

A look at the shelves of a major library awakens doubts in the author of this small volume about the importance of writing a new introduction to peptide synthesis. This rather narrow area of bio-organic chemistry already has received considerable attention. A whole series of books deals with the synthesis of peptides. Some of these are textbooks written to support lecture courses on peptide synthesis. Others try to help the beginner, otherwise well versed in organic chemistry, to embark on some experimental project that requires the construction of peptide chains. Not less useful are the monographs which were compiled to aid the adept practitioner and to provide him with references to the growing literature of a very active field. Is there any need for a new book on peptide synthesis? Should we add a new volume to an already impressive and certainly useful series? The answer is not obvious. The author has already participated in two similar en­ deavors. The first edition! of "Peptide Synthesis", with M. A. Ondetti as coauthor, was meant to serve as an introduction for the beginner. It was rather well received by researchers who joined the field of peptide chemistry and were looking for initiation. While working on the 2 second edition with Drs. Klausner and Ondetti, we became painfully aware of the impossibility of the task.

Authors and Affiliations

  • Department of Chemistry, Case Western Reserve University, Cleveland, USA

    Miklos Bodanszky

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