© 2003

Protein Complexes that Modify Chromatin

  • J. L. Workman

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 274)

About this book


Chromatin dynamics is a consequence of protein complexes that modify histones, remove histone modifications, mobilize nucleosomes or stabilize nucleosomes. A wide variety of such complexes have now been described. Some are abundant and may play global roles, others are more rare and specialized for functions at discreet loci. Several complexes share biochemical activities and genetic studies suggest overlapping functions. Many components of these complexes were first revealed in genetic screens, while others were discovered by novel biochemical approaches. This volume of Current Topics in Microbiology and Immunology reviews a wide variety of protein complexes that modify chromatin.


Chromosom DNA Elongation biology chromatin chromatin dynamics chromosome gene expression genes heterochromatin complexes histone acetyltransferase complexes protein protein complexes proteins transcription

Editors and affiliations

  • J. L. Workman
    • 1
  1. 1.Howard Hughes Medical Institute Department of Biochemistry and Molecular BiologyThe Pennsylvania State UniversityUniversity ParkUSA

Bibliographic information

  • Book Title Protein Complexes that Modify Chromatin
  • Editors Jerry L. Workman
  • Series Title Current Topics in Microbiology and Immunology
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-44208-0
  • Softcover ISBN 978-3-642-62909-9
  • eBook ISBN 978-3-642-55747-7
  • Series ISSN 0070-217X
  • Edition Number 1
  • Number of Pages XI, 298
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Human Genetics
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


From the reviews:

"This volume of Current Topics in Microbiology and Immunology entitled ‘Protein Complexes that Modify Chromatin’ takes the reader on a detailed voyage through chromatin. … The book is divided into ten chapters, each contributed by experts in the field of chromatin. … presents a detailed overview of the protein complexes that associates with chromatin. … is a great reference for researchers who are specifically interested in chromatin and its associated proteins."(Yassmine Akkari, The Journal of the Association of Genetic Technologists, Vol. 30 (1), 2004)

"This book provides timely reviews of several protein complexes that regulate gene expression and chromatin dynamics. Examples of such complexes include nucleosome assembly complexes, ATP-dependent chromatin remodeling complexes … . These chapters will bring experts in the field up to date on several aspects of chromosome biology and will provide an exciting introduction to the field for new chromatin researchers." (Journal of Investigational Allergology & Clinical Immunology, Vol. 13 (3), 2003)