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Xenotransplantation

  • Book
  • © 2003

Overview

Editors:
  1. Daniel R. Salomon

    1. Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, USA

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  2. Carolyn Wilson

    1. Division of Cellular and Gene Therapies Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Bethesda, USA

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 278)

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Table of contents (9 chapters)

  1. Front Matter

    Pages I-XIII
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  2. Genetic Modification of Xenografts

    • J. L. Platt
    Pages 1-21

  3. Xenotransplantation: Public Health Risks—Patient vs. Society in an Emerging Field

    • L. E. Chapman
    Pages 23-45

  4. Cross-Species Infections

    • R. A. Weiss
    Pages 47-71

  5. Nonhuman Primate Herpesviruses:Importance for Xenotransplantation

    • M. G. Michaels
    Pages 73-100

  6. Understanding Xenotransplantation Risks from Nonhuman Primate Retroviruses

    • J. S. Allan
    Pages 101-123

  7. Exogenous Porcine Viruses

    • P. S. Paul, P. Halbur, B. Janke, H. Joo, P. Nawagitgul, J. Singh et al.
    Pages 125-183

  8. Swine Hepatitis E Virus: Cross-Species Infection and Risk in Xenotransplantation

    • X. J. Meng
    Pages 185-216

  9. Molecular Cloning and Functional Characterization of Infectious PERV and Development of Diagnostic Tests

    • M. Niebert, R.R Tönjes
    Pages 217-237

  10. Xenotransplantation—Federal Regulatory Considerations

    • E. T. Bloom
    Pages 239-251

  11. Back Matter

    Pages 253-257
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Keywords

About this book

Xenotransplantation could have an impact on at least three aspects of medicine. The first is as a means of overcoming a severe shortage of human donor organs for the treatment of organ failure. The second aspect relates to the possibility that a xenogeneic organ would not be susceptible to infection by a "human" virus and thus the xenograft might resist injury caused by such viruses. The third and, as of yet, unexplored aspect relates to a means of delivering genes for therapeutic purposes thus overcoming some of the limitations of "conventional" gene therapy.     

Editors and Affiliations

  • Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, USA

    Daniel R. Salomon

  • Division of Cellular and Gene Therapies Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Bethesda, USA

    Carolyn Wilson

Bibliographic Information

  • Book Title: Xenotransplantation

  • Editors: Daniel R. Salomon, Carolyn Wilson

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-55541-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2003

  • Hardcover ISBN: 978-3-540-00210-9Published: 23 July 2003

  • Softcover ISBN: 978-3-642-62431-5Published: 13 September 2012

  • eBook ISBN: 978-3-642-55541-1Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XIII, 257

  • Topics: Immunology, Surgery

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma

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