Type IV Secretion in Gram-Negative and Gram-Positive Bacteria

  • Steffen Backert
  • Elisabeth Grohmann

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 413)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Peter J. Christie, Laura Gomez Valero, Carmen Buchrieser
    Pages 1-30
  3. Laurent Terradot, Célia Bergé, Gabriel Waksman
    Pages 31-60
  4. Kerstin Stingl, Günther Koraimann
    Pages 61-92
  5. Ellen L. Zechner, Gabriel Moncalián, Fernando de la Cruz
    Pages 93-113
  6. Matxalen Llosa, Itziar Alkorta
    Pages 143-168
  7. Hubert Hilbi, Hiroki Nagai, Tomoko Kubori, Craig R. Roy
    Pages 221-242
  8. Melanie M. Callaghan, Jan-Hendrik Heilers, Chris van der Does, Joseph P. Dillard
    Pages 323-345

About this book


Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.


Gram-negative bacteria Intracellular lifestyle Legionella Bartonella infections Helicobacter pylori Membrane-associated transporter complexes Gram-positive bacteria Eukaryotic cells Interbacterial transfer Antibiotic resistance T4SS

Editors and affiliations

  • Steffen Backert
    • 1
  • Elisabeth Grohmann
    • 2
  1. 1.Division of Microbiology, Department of BiologyFriedrich Alexander University Erlangen-NurembergErlangenGermany
  2. 2.Division of Microbiology, Faculty of Life Sciences and TechnologyBeuth University of Applied Sciences BerlinBerlinGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-75241-9
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-75240-2
  • Online ISBN 978-3-319-75241-9
  • Series Print ISSN 0070-217X
  • Series Online ISSN 2196-9965
  • About this book
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