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Type IV Secretion in Gram-Negative and Gram-Positive Bacteria

  • Book
  • © 2017

Overview

Editors:
  1. Steffen Backert

    1. Division of Microbiology, Department of Biology, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany

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  2. Elisabeth Grohmann

    1. Division of Microbiology, Faculty of Life Sciences and Technology, Beuth University of Applied Sciences Berlin, Berlin, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Offers new insights into the variety and structural diversity of type IV secretion systems
  • Provides information on bacterial colonization and disease development
  • Sheds new light on the manipulation of host cell functions by various pathogens

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 413)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xxii
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  2. Biological Diversity and Evolution of Type IV Secretion Systems

    • Peter J. Christie, Laura Gomez Valero, Carmen Buchrieser
    Pages 1-30

  3. Structural and Molecular Biology of Type IV Secretion Systems

    • Célia Bergé, Gabriel Waksman, Laurent Terradot
    Pages 31-60

  4. Prokaryotic Information Games: How and When to Take up and Secrete DNA

    • Kerstin Stingl, Günther Koraimann
    Pages 61-92

  5. Relaxases and Plasmid Transfer in Gram-Negative Bacteria

    • Ellen L. Zechner, Gabriel Moncalián, Fernando de la Cruz
    Pages 93-113

  6. Mechanisms of Conjugative Transfer and Type IV Secretion-Mediated Effector Transport in Gram-Positive Bacteria

    • Elisabeth Grohmann, Walter Keller, Günther Muth
    Pages 115-141

  7. Coupling Proteins in Type IV Secretion

    • Matxalen Llosa, Itziar Alkorta
    Pages 143-168

  8. Type IV Secretion in Agrobacterium tumefaciens and Development of Specific Inhibitors

    • Mahzad Sharifahmadian, Christian Baron
    Pages 169-186

  9. The Helicobacter pylori Type IV Secretion System Encoded by the cag Pathogenicity Island: Architecture, Function, and Signaling

    • Steffen Backert, Rainer Haas, Markus Gerhard, Michael Naumann
    Pages 187-220

  10. Subversion of Host Membrane Dynamics by the Legionella Dot/Icm Type IV Secretion System

    • Hubert Hilbi, Hiroki Nagai, Tomoko Kubori, Craig R. Roy
    Pages 221-242

  11. Beginning to Understand the Role of the Type IV Secretion System Effector Proteins in Coxiella burnetii Pathogenesis

    • Anja Lührmann, Hayley J. Newton, Matteo Bonazzi
    Pages 243-268

  12. Type IV Effector Secretion and Subversion of Host Functions by Bartonella and Brucella Species

    • Christoph Dehio, Renée M. Tsolis
    Pages 269-295

  13. Role and Function of the Type IV Secretion System in Anaplasma and Ehrlichia Species

    • Yasuko Rikihisa
    Pages 297-321

  14. Secretion of Chromosomal DNA by the Neisseria gonorrhoeae Type IV Secretion System

    • Melanie M. Callaghan, Jan-Hendrik Heilers, Chris van der Does, Joseph P. Dillard
    Pages 323-345

  15. Erratum to: Type IV Secretion in Gram-Negative and Gram-Positive Bacteria

    • Steffen Backert, Elisabeth Grohmann
    Pages E1-E1
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Keywords

About this book

Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.

Editors and Affiliations

  • Division of Microbiology, Department of Biology, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany

    Steffen Backert

  • Division of Microbiology, Faculty of Life Sciences and Technology, Beuth University of Applied Sciences Berlin, Berlin, Germany

    Elisabeth Grohmann

About the editors

Prof. Dr. rer. nat. Steffen Backert
Chair of Microbiology
Friedrich Alexander University Erlangen/Nuremberg
Department of Biology
Division of Microbiology
Staudtstr. 5
D-91058 Erlangen
Germany
Tel.  ++49 9131 8528081
Fax  ++49 9131 8528082 

Prof. Dr. techn. Elisabeth Grohmann
Professor of Microbiology
Beuth University of Applied Sciences Berlin
Department of Life Sciences and Technology
Division of Microbiology
Forum Seestraße
Seestr. 64
D-13347 Berlin
Germany
Tel. ++49 30 45043942
Fax ++49 30 45043983

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