Overview
- Includes updated profiles of SCF and APC cellular functions and their characterized ubiquitin substrates
- Introduces the emergent SCF family members in the human genome and summarizes phenotypes in which the adapter proteins of SCF and APC are manipulated to reflect the pathogenesis of human cancer
- Discusses how SCF and APC may represent promising therapeutic targets to treat various types of cancers
- Includes supplementary material: sn.pub/extras
Part of the book series: SpringerBriefs in Cancer Research (BRIEFSCANCER)
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Table of contents (6 chapters)
Keywords
About this book
Authors and Affiliations
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Bibliographic Information
Book Title: SCF and APC E3 Ubiquitin Ligases in Tumorigenesis
Authors: Hiroyuki Inuzuka, Wenyi Wei
Series Title: SpringerBriefs in Cancer Research
DOI: https://doi.org/10.1007/978-3-319-05026-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Author(s) 2014
Softcover ISBN: 978-3-319-05025-6Published: 08 April 2014
eBook ISBN: 978-3-319-05026-3Published: 28 March 2014
Series ISSN: 2194-1173
Series E-ISSN: 2194-1181
Edition Number: 1
Number of Pages: V, 118
Number of Illustrations: 11 illustrations in colour
Topics: Cancer Research, Cell Cycle Analysis, Protein Structure
Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma