Overview
- Provides a collection of robust protocols for molecular biologists studying comparative genomics
- Each chapter includes detailed instructions for using a particular tool or method and an introduction to the theory behind the technique
- A Notes section at the end of each chapter that guides the user through commonly encountered difficulties, providing key tips for using the method most efficiently
Part of the book series: Methods in Molecular Biology (MIMB, volume 396)
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About this book
Comparative Genomics, Volume 2, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume 2 contains the last three of seven sections. In the second volume, the fifth section describes a number of tools for comparative analysis of domain and gene families. These tools are particularly useful for predicting protein function as well as potential protein-protein interactions. In the sixth section, methods for comparing groups of genes and gene order are discussed, as are several tools for analyzing genome evolution. Finally, the seventh section deals with experimental comparative genomics. This section includes methods for comparing gene copy number across an entire genome, comparative genomic hybridization, SNP analysis, as well as genome-wide mapping and typing systems for bacterial genomes. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 1 is also available from Humana Press.
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Keywords
Table of contents (27 protocols)
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Comparative Analysis of Domain and Protein Families
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Orthologs, Synteny, and Genome Evolution
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Experimental Analysis of Whole Genomes: Analysis of Copy Number and Sequence Polymorphisms
Editors and Affiliations
Bibliographic Information
Book Title: Comparative Genomics
Book Subtitle: Volume 2
Editors: Nicholas H. Bergman
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-515-2
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2007
Hardcover ISBN: 978-1-934115-37-4Published: 29 November 2007
Softcover ISBN: 978-1-61737-933-8Published: 25 December 2011
eBook ISBN: 978-1-59745-515-2Published: 07 February 2008
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVIII, 434
Number of Illustrations: 150 b/w illustrations, 1 illustrations in colour
Topics: Biochemistry, general, Human Genetics, Cell Biology
Industry Sectors: Biotechnology, Consumer Packaged Goods, Pharma