Overview
- Editors:
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H. Hugh Fudenberg
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Medical University of South Carolina, Charleston, USA
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H. D. Whitten
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Medical University of South Carolina, Charleston, USA
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Fabio Ambrogi
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University of Pisa, Pisa, Italy
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About this book
On May 14-16, 1982, a group of scientists met in Viareggio, Italy to present ideas, and exchange relevant data on current approaches on immunomodulators. We felt that the embodiment of the substance of that international symposium into this volume will be beneficial in keeping both clinicians and basic scientists abreast of the latest exciting developments in this rapidly accelerating field. We hope that the publication of this series of papers by an international panel of experts will enhance the nature of future inves t igat ive stud ies with such ent it ies . Under the rubric of immunology, it is obvious that such a term as "immunomodulation" could be construed as being all encompassing. However, it is intriguing that the immune modulators touched on in these sessions can be subcategorized into about five broad groups. Almost all substances, excepting those entities that are immuno logically inert, will have some modulating effects on immunity. From the coarse adjustment of antibody feedback inhibition upon cellular limnunity to the subtle finesse envisioned in Jerne's idiotypic network and s'lppressor T cells, immunomodulators attempt to either magnify or diminish those responses that are normally elicited by antigen. The broad groups - thymic hormones, D.L.E., Interferon, drugs, and the use of bacterial products appear to be at the forefront of much of the pioneering work on immunomodulation.
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Table of contents (31 chapters)
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Thymus Hormone or Extracts
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- J.-L. Touraine, M. C. Favrot, M. El Ansary
Pages 1-8
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- Jacob Shoham, Abraham S. Klein
Pages 17-33
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- Mireille Dardenne, Jean-Francois Bach
Pages 35-42
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- M. G. Bernengo, F. Lisa, P. Fra, M. Meregalli, M. Novelli, G. Zina
Pages 43-67
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- P. Rambotti, A. Velardi, M. F. Martelli, C. Cernetti, F. Spinozzi, F. Grignani et al.
Pages 69-83
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Dialyzable Leukocyte Extracts and Immune RNA
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- John A. Mannick, Bosco S. Wang, Glenn D. Steele, Jerome P. Richie
Pages 85-104
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- Maria Caterina Sirianni, R. Paganelli
Pages 105-114
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- H. H. Fudenberg, G. B. Wilson, K. Y. Tsang
Pages 115-130
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Bacterial Products
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- Ruben A. Binaghi, Fabrizio Bruschi, Stella Maris Venturiello
Pages 197-208
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- Herman Friedman, Thomas Klein, R. Christopher Butler
Pages 209-228
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- Y. Daskal, C. A. Mattioli, D. S. Terman
Pages 229-247
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Cell Interactions
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- J. P. R. M. van Laarhoven, C. H. M. M. De Bruyn, H. Collet, G. Delespesse
Pages 257-267
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- M. Piantelli, P. Mussiani, L. Lauriola, N. Maggiano, F. O. Ranelletti
Pages 269-277
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- Martin Krönke, Klaus Pfizenmaier, Hermann Wagner
Pages 279-292