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Recent Data on the Structure, Localization and Function of the Serum Thymic Factor (Thymulin)

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Immunomodulation

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Abstract

The serum thymic factor (FTS) or thymulin is a thymic hormone which has been characterized by its capacity to induce T cell markers on bone marrow cells.1 It is a nonapeptide whose amino acid sequence has been determined.2 We have recently demonstrated the existence of two forms of FTS: the first one without zinc and biologically inactive, and another which binds zinc and is biologically active, for which we recently proposed the name of thymulin.3 Practically thymulin or FTS-Zn represents the natural zinc-coupled peptide; the use of “FTS” is reserved for the synthetic material not coupled to the metal.

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Authors and Affiliations

  1. Hopital Necker, INSERM U 25, 161 rue de Sevres, 75015, Paris, France

    Mireille Dardenne & Jean-Francois Bach

Authors
  1. Mireille Dardenne
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  2. Jean-Francois Bach
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Editors and Affiliations

  1. Medical University of South Carolina, Charleston, South Carolina, USA

    H. Hugh Fudenberg  & H. D. Whitten  & 

  2. University of Pisa, Pisa, Italy

    Fabio Ambrogi

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© 1984 Plenum Press, New York

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Dardenne, M., Bach, JF. (1984). Recent Data on the Structure, Localization and Function of the Serum Thymic Factor (Thymulin). In: Fudenberg, H.H., Whitten, H.D., Ambrogi, F. (eds) Immunomodulation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9358-4_4

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  • DOI: https://doi.org/10.1007/978-1-4615-9358-4_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9360-7

  • Online ISBN: 978-1-4615-9358-4

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