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Immunomodulation

New Frontiers and Advances

  • Book
  • © 1984

Overview

Editors:
  1. H. Hugh Fudenberg

    1. Medical University of South Carolina, Charleston, USA

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  2. H. D. Whitten

    1. Medical University of South Carolina, Charleston, USA

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  3. Fabio Ambrogi

    1. University of Pisa, Pisa, Italy

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Table of contents (31 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Thymus Hormone or Extracts

    1. Role of Thymic Factors and of Thymic Epithelial Cells in Human T Lymphocyte Differentiation

      • J.-L. Touraine, M. C. Favrot, M. El Ansary
      Pages 1-8

    2. Thymic Hormone Therapy of Primary Immunodeficiency Diseases

      • M. Fiorilli
      Pages 9-15

    3. The Effect of the Thymic Extract Thymostimulin (TP-1) in Experimental Models of Cancer and Viral Infections

      • Jacob Shoham, Abraham S. Klein
      Pages 17-33

    4. Recent Data on the Structure, Localization and Function of the Serum Thymic Factor (Thymulin)

      • Mireille Dardenne, Jean-Francois Bach
      Pages 35-42

    5. In Vitro and In Vivo Effect of Thymostimulin in Melanoma Patients

      • M. G. Bernengo, F. Lisa, P. Fra, M. Meregalli, M. Novelli, G. Zina
      Pages 43-67

    6. The Effect of Thymostimulin on the Immunologic Parameters of Patients with Untreated Hodgkin’s Disease

      • P. Rambotti, A. Velardi, M. F. Martelli, C. Cernetti, F. Spinozzi, F. Grignani et al.
      Pages 69-83

  3. Dialyzable Leukocyte Extracts and Immune RNA

    1. Laboratory and Clinical Experience with the Transfer of Tumor Immunity with Immune RNA

      • John A. Mannick, Bosco S. Wang, Glenn D. Steele, Jerome P. Richie
      Pages 85-104

    2. In Vitro and In Vivo Effects of Dialyzable Leukocyte Extracts (DLE)

      • Maria Caterina Sirianni, R. Paganelli
      Pages 105-114

    3. Evaluation of “Transfer Factor” Potency and Prediction of Clinical Response

      • H. H. Fudenberg, G. B. Wilson, K. Y. Tsang
      Pages 115-130

  5. Bacterial Products

    1. Immunomodulation in Parasitic Diseases

      • Ruben A. Binaghi, Fabrizio Bruschi, Stella Maris Venturiello
      Pages 197-208

    2. Bacterial Antigens as Immunomodulators

      • Herman Friedman, Thomas Klein, R. Christopher Butler
      Pages 209-228

    3. Comparative Morphologic Changes in Canine and Human Breast Adenocarcinoma After Treatment with Plasma Perfused Over Immobilized Protein A

      • Y. Daskal, C. A. Mattioli, D. S. Terman
      Pages 229-247

    4. Cancer Immunotherapy in Japan

      • Y. Yamamura, I. Azuma
      Pages 249-256

  6. Cell Interactions

    1. Differential In Vitro Effects of Adenosine and Deoxyadenosine on Human T- and B-Lymphocyte Function

      • J. P. R. M. van Laarhoven, C. H. M. M. De Bruyn, H. Collet, G. Delespesse
      Pages 257-267

    2. Modulation of Human T-Lymphocyte Mitogenesis by Interleukin 1 and Glucocorticoids

      • M. Piantelli, P. Mussiani, L. Lauriola, N. Maggiano, F. O. Ranelletti
      Pages 269-277

    3. Functional Analysis of Alloreactive Helper T Cells Involved in the Induction of Cytolytic T Cell Responses In Vitro

      • Martin Krönke, Klaus Pfizenmaier, Hermann Wagner
      Pages 279-292
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Keywords

About this book

On May 14-16, 1982, a group of scientists met in Viareggio, Italy to present ideas, and exchange relevant data on current approaches on immunomodulators. We felt that the embodiment of the substance of that international symposium into this volume will be beneficial in keeping both clinicians and basic scientists abreast of the latest exciting developments in this rapidly accelerating field. We hope that the publication of this series of papers by an international panel of experts will enhance the nature of future inves t igat ive stud ies with such ent it ies . Under the rubric of immunology, it is obvious that such a term as "immunomodulation" could be construed as being all encompassing. However, it is intriguing that the immune modulators touched on in these sessions can be subcategorized into about five broad groups. Almost all substances, excepting those entities that are immuno­ logically inert, will have some modulating effects on immunity. From the coarse adjustment of antibody feedback inhibition upon cellular limnunity to the subtle finesse envisioned in Jerne's idiotypic network and s'lppressor T cells, immunomodulators attempt to either magnify or diminish those responses that are normally elicited by antigen. The broad groups - thymic hormones, D.L.E., Interferon, drugs, and the use of bacterial products appear to be at the forefront of much of the pioneering work on immunomodulation.

Editors and Affiliations

  • Medical University of South Carolina, Charleston, USA

    H. Hugh Fudenberg, H. D. Whitten

  • University of Pisa, Pisa, Italy

    Fabio Ambrogi

Bibliographic Information

  • Book Title: Immunomodulation

  • Book Subtitle: New Frontiers and Advances

  • Editors: H. Hugh Fudenberg, H. D. Whitten, Fabio Ambrogi

  • DOI: https://doi.org/10.1007/978-1-4615-9358-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1984

  • Softcover ISBN: 978-1-4615-9360-7Published: 05 February 2012

  • eBook ISBN: 978-1-4615-9358-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: X, 458

  • Topics: Immunology

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma

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