Skip to main content
SpringerLink
Log in

Mechanisms of Environmental Mutagenesis-Carcinogenesis

  • Book
  • © 1990

Overview

Editors:
  1. Andreas Kappas

    1. Institute of Biology, National Research Center “Democritus”, Athens, Greece

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (22 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Mutations and Carcinogenicity

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Mutation Spectrum in Carcinogenicity

      • Claes Ramel
      Pages 3-24

  3. Mechanisms of Chemically-Induced Genetic Effects on Molecular, Chromosomal and Cell Division Level

    1. Front Matter

      Pages 25-25
      Download chapter PDF

    2. Ultraviolet Light Mutagenesis in Bacteria: The Possible Role of a DNA Polymerase III Complex Lacking Proofreading Exonuclease

      • B. A. Bridges
      Pages 27-35

    3. Centromere Separation: Emerging Relationship with Aneuploidy

      • Baldev K. Vig, Neidhard Paweletz
      Pages 37-48

    4. Genetic Analysis of Genotoxic Effects on Chromosomes and Cell Division in Lower Eukaryotes

      • Etta Kafer, Andreas Kappas
      Pages 49-68

    5. DNA Repair and the Recombination Barrier Between Divergent (Homologous) Chromosomes

      • Michael A. Resnick, Torsten Nilsson-Tillgren
      Pages 69-74

    6. Consequences of Altering Tubulin Levels in Yeast

      • Brant Weinstein, Frank Solomon
      Pages 75-85

    7. A Genetic Assay Using Rodent/Human Hybrid Cells to Evaluate the Genotoxic Effects of Chemicals for Multiple Endpoints

      • Shahbeg S. Sandhu, Ramadevi Gudi, Raghbir S. Athwal
      Pages 87-95

    8. Aneuploidy in Humans

      • Judith H. Ford
      Pages 97-114

  4. Adaptability and Repair Mechanisms

    1. Front Matter

      Pages 115-115
      Download chapter PDF

    2. The Adaptive Response to Alkylation Damage in Escherichia Coli

      • Barbara Sedgwick
      Pages 117-128

    3. The Adaptive Response of Human Lymphocytes to Radiation or Chemical Mutagens: Cross-Adaptation and Synergism

      • Sheldon Wolff, Gregorio Olivieri, Veena Afzal
      Pages 129-137

    4. Evolving Mutation Rates and Prospects for Antimutagenesis

      • John W. Drake
      Pages 139-149

    5. Genetic Analysis of DNA Repair Defect in Xeroderma Pigmentosum Cells: Identification of Complementing Genes

      • Gursurinder P. Kaur, Raghbir S. Athwal
      Pages 151-163
Back to top

Keywords

About this book

The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta­ tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical­ ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens­ able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi­ tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.

Editors and Affiliations

  • Institute of Biology, National Research Center “Democritus”, Athens, Greece

    Andreas Kappas

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation