Abstract
DNA is subject to damage by a variety of physical and chemical carcinogens. Through evolution, the environment has selected organisms having very efficient repair systems that eliminate much of the damaged DNA. Considerable progress has been made in understanding repair processes in procaryotes and lower eukaryotes and genes involved in several of the various repair pathways have been cloned (See Review in Friedberg, 1985). However, very little is known about the details of biochemical events involved in repair of DNA damage in human cells.
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Kaur, G.P., Athwal, R.S. (1990). Genetic Analysis of DNA Repair Defect in Xeroderma Pigmentosum Cells: Identification of Complementing Genes. In: Kappas, A. (eds) Mechanisms of Environmental Mutagenesis-Carcinogenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3808-0_12
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DOI: https://doi.org/10.1007/978-1-4615-3808-0_12
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