Correction to: Journal of Pharmacokinetics and Pharmacodynamics (2018) 45:S3–S134 https://doi.org/10.1007/s10928-018-9606-9

The original version of this article unfortunately contained a mistake under the heading “T-029”.

In Table 1, the “Variables” in the last row has been replaced. Please find below the corrected Table 1.

Table 1 Exposure response final model results
Full size table

The last paragraph before conclusions read as:

AGE: age; ASN1 = Asian; BCHOL: baseline cholesterol; BTG = baseline triglycerides; BWT = baseline body weight; CAUCcomplete: calculated cumulative AUC over a complete cycle using maximum total daily dose, individual estimates of bioavailability, and individual estimates of maximum clearance; CI = confidence interval; Cmax event: maximum observed concentration prior to the adverse event; DAY1: time to event (days); DD = change in deviance; Estimate = the estimated coefficient, which is equal to the natural log of the odds ratio; NCON1: concomitant narcotic use; n/N = number of patients used in the final model/total number of patients; Odds Ratio = the odds of the event occurring, over the odds of the event not occurring; p[|z|= the tail area in a 2-tail test; SCON1: concomitant steroid use; TEAE = treatment emergent adverse event.


Please find below the corrected text:

ASN1 = Asian; BCHOL: baseline cholesterol; BTG = baseline triglycerides; BWT = baseline body weight; Ctrough ss: steady state trough concentration; CI = confidence interval; Cmax event: maximum observed concentration prior to the adverse event; DAY1: time to event (days); ΔD = change in deviance; Estimate = the estimated coefficient, which is equal to the natural log of the odds ratio; n/N = number of patients used in the final model/total number of patients; Odds Ratio = the odds of the event occurring, over the odds of the event not occurring; p >|z|= the tail area in a 2-tail test; TEAE = treatment emergent adverse event.

The original article has been corrected.