Abstract
Polycyclic aromatic hydrocarbons (PAHs) are worldwide pollutants produced mainly during incomplete combustion and pyrolysis of organic substances. PAH derivatives are components with hydrogen on the aromatic ring substituted by carbonyl-, nitro- and hydroxyl-functional groups (N-PAH, O-PAH or OH-PAH), or a group of heterocyclic PAHs containing one sulfur atom in place of a carbon atom in the aromatic ring. PAHs and their derivatives can be either introduced in the atmosphere directly in this form as primary pollutants, or formed by homogenous and heterogeneous oxidation reactions. During the last decades, interest on studying PAH derivatives has increased because derivatives may be more harmful than parent compounds. PAH derivatives have been detected in the atmospheric particulate matter in numerous cities worldwide. PAH derivatives enter living organisms by inhalation, oral ingestion and dermal contact. In vivo and in vitro experiments together with epidemiological studies have shown the toxic effects of PAH derivatives, notably for compounds present in airborne and diesel exhaust particles. Here we review the sources, the mechanisms of formation, the physicochemical properties, the analytical methods, and the toxicological effects of PAHs and their derivatives in airborne particulate matter.
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Abbreviations
- AhR:
-
Aryl hydrocarbon receptor
- APSE:
-
Accelerated/pressurized solvent extraction
- B[a]P:
-
Benzo[a]pyrene
- CLD:
-
Chemiluminescence detector
- CPAHs:
-
Combustion-related PAHs
- DPM:
-
Diesel particulate matter
- ECD:
-
Electron capture detector
- GC–EI/MS:
-
Gas chromatography–electron impact/mass spectrometry
- GC:
-
Gas chromatography
- HFBA:
-
Heptafluorobutyric anhydride
- HPLC:
-
High-performance liquid chromatography
- LC-APCI/MS:
-
Liquid chromatography–atmospheric pressure chemical ionization/mass spectrometry
- LOH:
-
Loss of heterozygosity
- MAE:
-
Microwave-assisted extraction
- MDA:
-
Malonaldehyde
- MN:
-
Micronuclei
- MS:
-
Mass spectrometry
- N-PAHs:
-
Nitrated PAHs
- NA:
-
Nuclear abnormalities
- NCD:
-
Nitrogen chemiluminescence detector
- NCI-MS:
-
Ion chemical ionization mass spectrometry
- NICI:
-
Negative ion chemical ionization
- NPD:
-
Nitrogen and phosphorus selective detector
- O-PAHs:
-
Oxygenated PAHs
- Oct-4:
-
Octamer-4
- OH-PAHs:
-
Hydroxylated PAHs
- PASHs:
-
Sulfur heterocycles PAHs
- PFE:
-
Pressurized fluid extraction
- PM:
-
Particulate matter
- QuEChERS:
-
Quick easy cheap effective rugged and safe
- SE:
-
Solvent extraction
- SFE:
-
Supercritical fluid extraction
- SIM:
-
Selective ion monitoring
- TID:
-
Thermionic ionization detector
- TPAHs:
-
Total PAHs
- TSP:
-
Total suspended particles
- UE:
-
Ultrasonic extraction
- USEPA:
-
United States Environmental Protection Agency
- XME:
-
Xenobiotic-metabolizing enzyme
- XRE:
-
Xenobiotic element response
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Acknowledgements
This work was supported by the National Council of Scientific Research in Lebanon, especially the Lebanese Atomic Energy Commission. The “Unité de Chimie Environnementale et Interactions sur le Vivant” (UCEIV-EA4492) and the “IMPacts de l’Environnement Chimique sur la Santé Humaine” (IMPECS-EA4483) both participate in the CLIMIBIO project, which is financially supported by the Hauts-de-France Region Council, the French Ministry of Higher Education and Research, and the European Regional Development Funds.”
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Abbas, I., Badran, G., Verdin, A. et al. Polycyclic aromatic hydrocarbon derivatives in airborne particulate matter: sources, analysis and toxicity. Environ Chem Lett 16, 439–475 (2018). https://doi.org/10.1007/s10311-017-0697-0
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DOI: https://doi.org/10.1007/s10311-017-0697-0