Serpiginous Choroiditis

  • Aniruddha Agarwal
  • Quan Dong Nguyen
  • Vishali Gupta
Living reference work entry


Serpiginous choroiditis is a rare, usually bilateral, chronic, recurrent inflammation that affects the outer retina and the inner choroid. The exact etiology of serpiginous choroiditis is still unknown; however, the disease is considered to be autoimmune in nature. The disease usually manifests as geographic, helicoid, or placoid choroiditis lesions that continue to progress in a serpentine manner. Fluorescein angiography, indocyanine green angiography, and optical coherence tomography are very useful in determining the activity of the disease and monitoring the response to therapy. Systemic corticosteroids and immunosuppressive agents are the mainstay of therapy for serpiginous choroiditis. The index chapter illustrates two cases of serpiginous choroiditis with characteristic morphological appearance.


Optical Coherence Tomography Retinal Pigment Epithelium Fluorescein Angiography Imaging Optical Coherence Tomography Choroidal Neovascularization 
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Suggested Reading

  1. Bansal R, Gupta A, Gupta V. Imaging in the diagnosis and management of serpiginous choroiditis. Int Ophthalmol Clin. 2012;52:229–36.CrossRefPubMedGoogle Scholar
  2. Lim WK, Buggage RR, Nussenblatt RB. Serpiginous choroiditis. Surv Ophthalmol. 2005;50:231–44.CrossRefPubMedGoogle Scholar
  3. Nazari Khanamiri H, Rao NA. Serpiginous choroiditis and infectious multifocal serpiginoid choroiditis. Surv Ophthalmol. 2013;58:203–32.CrossRefPubMedGoogle Scholar

Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Advanced Eye CenterPost Graduate Institute of Medical Education and Research (PGIMER)ChandigarhIndia
  2. 2.Stanley M. Truhlsen Eye InstituteUniversity of Nebraska Medical CenterOmahaUSA

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