Uveitis, particularly intermediate or posterior uveitis, is often complicated by the presence of cystoid macular edema (CME) that causes significant visual loss. Fundus fluorescein angiography plays an important role in demonstrating cystoid macular edema and co-existing manifestations of active uveitis. Optical coherence tomography helps in monitoring response to therapy. Treatment of uveitic macular edema involves the use of corticosteroids as standard of care by topical, periocular, intravitreal, oral or intravenous route, depending upon the severity of edema and laterality. Anti-vascular endothelial growth factor therapy is a good alternative in uveitic cystoid macular edema. Immunosuppressive agents may be indicated in refractory CME.
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