Band Shaped Keratopathy

Living reference work entry


Band-shaped keratopathy (BSK) describes a band of calcium salt precipitated across the Bowman layer of cornea. Calcium precipitation is thought to be favored by interpalpebral tear evaporation, systemic hypercalcemia, and elevated pH (e.g., with uveitis). BSK is associated with various conditions including uveitis, corneal edema, phthisis bulbi, end stage glaucoma, and systemic hypercalcemic states but is often idiopathic. Patients may complain of ocular irritation or blurry vision. Diagnosis is based on slit-lamp examination showing a central gray-white corneal plaque that sometimes spares the periphery. BSK may be treated with EDTA chelation with or without debridement when it causes visual disturbance, obstructs intraocular view required for examination or surgery, or is symptomatic. The underlying cause should be sought and treated first to prevent recurrence.


Proliferative Diabetic Retinopathy Juvenile Rheumatoid Arthritis Cystoid Macular Edema Corneal Edema Prednisolone Acetate 
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Suggested Reading

  1. Anderson DF, Prabhasawat P, Alfonso E, Tseng SCG. Amniotic membrane transplantation after the primary surgical management of band keratopathy. Cornea. 2001;20(4):354–61.CrossRefPubMedGoogle Scholar
  2. Jhanji V, Rapuano CJ, Vajpayee RB. Corneal calcific band keratopathy. Curr Opin Ophthalmol. 2011;22(4):283–9.CrossRefPubMedGoogle Scholar
  3. Johnston RL, Stanford MR, Verma S, Green WT, Graham EM. Resolution of calcific band keratopathy after lowering elevated serum calcium in a patient with sarcoidosis. Br J Ophthalmol. 1995;79:1050–6.CrossRefPubMedPubMedCentralGoogle Scholar
  4. Najjar DM, Cohen EJ, Rapuano CJ, Laibson PR. EDTA chelation for calcific band keratopathy: results and long-term follow-up. Am J Ophthalmol. 2004;137(6):1056–64.CrossRefPubMedGoogle Scholar

Copyright information

© Springer (India) Pvt. Ltd. 2016

Authors and Affiliations

  1. 1.Institute of Ophthalmology and Visual ScienceNew Jersey Medical School, Rutgers University, Doctors Office CenterNewarkUSA
  2. 2.Metropolitan Eye Research and Surgery InstitutePalisades ParkUSA

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