Nodular Anterior Scleritis

Living reference work entry


Nodular scleritis presents with a nodule (or nodules) that is firm, immobile, and tender to palpation. The nodule varies from yellow to deep red, depending on the local vascular congestion and is usually in the interpalpebral zone, close to the limbus (but can occur anywhere). The underlying sclera may become transparent, but not necrotic. As over 10 % of nodular scleritis will progress to necrotizing scleritis. An associated systemic disease may be found in up to 30 % of patients, most commonly rheumatoid arthritis but also anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Early diagnosis and prompt treatment not only prevent ocular complications, but also may prolong survival by halting the progression of the underlying systemic disease.


Rheumatoid Arthritis Systemic Lupus Erythematosus Optical Coherence Tomography Anterior Uveitis Ocular Examination 
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Suggested Reading

  1. Sainz de la Maza M, Tauber J, Foster CS. The sclera. 2nd ed. New York: Springer; 2012.Google Scholar
  2. Watson PG, Hazleman BL, McCluskey P, Pavesio CE. The sclera and systemic disorders. 3rd ed. London: JP Medical; 2012.Google Scholar

Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Clinical Institute of Ophthalmology, Hospital Clinic of BarcelonaCentral University of BarcelonaBarcelonaSpain

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