ATF2, Fig. 1

Schematic presentation of the ATF2 family protein. Structural, functional domains and comparison of ATF2 family are shown. The leucine zipper domain contains a basic region mediating sequence-specific DNA binding followed by a leucine zipper region required for dimerization. Both the regions of the metal finger structure are required for transactivation. Serine 62, 340, 367, 472, 480, 490, 498 and theronine 69, 71, 72 residues may influence ATF2 signaling by acting as phosphorylated domain