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Cognitive and Behavioral Aspects of Childhood Hypertension

Pediatric Hypertension

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Abstract

Young hypertensive adults demonstrate decreased performance on neurocognitive testing compared with that of normotensive controls. There is emerging evidence that children with hypertension also manifest cognitive differences when compared to normotensive controls. Findings from studies of cognition in young adults have important implications for the study of cognition in hypertensive children. Recent studies suggest that both children with primary hypertension and children with hypertension secondary to chronic kidney disease have decreased performance on neurocognitive testing. Furthermore, children with primary hypertension have an increased prevalence of learning disabilities. Potential mechanisms include blunted cerebrovascular reactivity in hypertensive children. Ongoing studies of cognition in children with primary hypertension will further define the emerging hypertension-cognition link in youth.

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Authors and Affiliations

  1. Department of Pediatrics, Division of Pediatric Nephrology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 777, Rochester, NY, 14642, USA

    Marc B. Lande

  2. Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, Maimonides Infants and Children’s Hospital, 977 48th Street, Brooklyn, NY, 11219, USA

    Juan C. Kupferman

  3. Department of Neurology, Division of Child Neurology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 631, Rochester, NY, 14642, USA

    Heather R. Adams

Authors
  1. Marc B. Lande
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  2. Juan C. Kupferman
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  3. Heather R. Adams
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Corresponding author

Correspondence to Marc B. Lande .

Editor information

Editors and Affiliations

  1. Division of Nephrology, Seattle Children's Hospital, Seattle, Washington, USA

    Joseph Flynn

  2. Massachusetts General Hospital, Boston, Massachusetts, USA

    Julie R. Ingelfinger

  3. Arkansas Children's Hospital, University of Arkansas Medical Science, Little Rock, Arkansas, USA

    Karen Redwine

Section Editor information

  1. Division of Nephrology, Seattle Children’s Hospital, 4800 Sand Point Way NE, 98105, Seattle, WA, USA

    Joseph T. Flynn MD, MS

  2. Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA

    Joseph T. Flynn MD, MS

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Lande, M.B., Kupferman, J.C., Adams, H.R. (2016). Cognitive and Behavioral Aspects of Childhood Hypertension. In: Flynn, J., Ingelfinger, J., Redwine, K. (eds) Pediatric Hypertension. Springer, Cham. https://doi.org/10.1007/978-3-319-31420-4_30-1

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  • DOI: https://doi.org/10.1007/978-3-319-31420-4_30-1

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  • Online ISBN: 978-3-319-31420-4

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Chapter history

  1. Latest

    Neurocognition in Childhood Hypertension
    Published:
    24 May 2022

    DOI: https://doi.org/10.1007/978-3-319-31420-4_30-2

  2. Original

    Cognitive and Behavioral Aspects of Childhood Hypertension
    Published:
    13 December 2016

    DOI: https://doi.org/10.1007/978-3-319-31420-4_30-1

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