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Pathogenesis of Microvascular Complications

  • Mogher Khamaisi
  • George L. King
  • Kyoungmin Park
  • Qian Li
Living reference work entry
Part of the Endocrinology book series (ENDOCR)

Abstract

Risk factors and protective factors in diabetic microvascular complication.

Keywords

Advanced glycation end products (AGE) Reactive oxygen species (ROS) Protein kinase C (PKC) Vascular endothelial growth factor (VEGF) Activated protein C (APC) Platelet-derived growth factor (PDGF) Transforming growth factor b (TGF) Heme qxygenase-1 (HO-1) 

Notes

Acknowledgement

The authors would like to acknowledge funding from the Juvenile Diabetes Research Foundation grant 17-2011-474, National Institutes of Health grants 5 R01 DK053105-12, 5 R24 DK090961-02, 1 DP3 DK094333-01, NIH Diabetes Research Center 2 P30 DK036836-26A1, ADA mentor-based fellowship.

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Mogher Khamaisi
    • 1
    • 2
  • George L. King
    • 1
  • Kyoungmin Park
    • 1
  • Qian Li
    • 1
  1. 1.Section of Vascular Cell Biology, Joslin Diabetes CenterHarvard Medical SchoolBostonUSA
  2. 2.Institutes of Endocrinology, Diabetes and Metabolism and Internal Medicine DRambam Health Care Campus and RB Rappaport Faculty of Medicine-TechnionHaifaIsrael

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