Abstract
Dermis consists mostly of protein fibers and extracellular matrix. Hyaluronic acid (HA) is an abundant glycosaminoglycan, natural compound of dermal extracellular matrix, with high affinity to water. This characteristic is determinant of skin viscoelasticity, hydration, structure, and firmness.
During aging process, collagenesis and elastogenesis are diminished, there are disorganization and degradation of dermic fibers and, finally, it is observed reduced glycosaminoglycans. These phenomena result in reduction of elasticity, density, and resistance of the skin.
Skin booster is a new concept of treatment which promotes a global improvement of the skin, by HA injections in dermis. The objective of this approach is to maintain skin hydration, delaying or reversing aging process, reducing aging indicators associated with loss of mechanical properties, and using small quantities of HA. It can be indicated to young or elderly people, preventing or treating senescence signs.
It is known that, after injected in dermis, HA improve hydration and stimulate collagen production, by mechanical tension, consequent to stretched fibers.
In this chapter, some aspects of physiological behavior of HA and how it takes part in aging process and skin booster treatment will be discussed.
This is a preview of subscription content, log in via an institution to check access.
References
Distante F, Pagani V, Bonfigli A. Stabilized HA of non-animal origin for rejuvenating the skin of the upper arm. Dermatol Surg. 2009;35:389–94. doi:10.1111/j.1524-4725.2008.01051.x.
Edsman K, Nord LI, Ohrlund A, Larkner H, Kenne AH. Gel properties of HA dermal fillers. Dermatol Surg. 2012;38:1170–9. doi:10.1111/j.1524-4725.2012.02472.x.
Fabi SG, Goldman MP. Hand rejuvenation: a review and our experience. Dermatol Surg. 2012;38:1112–27. doi:10.1111/j.1524-4725.2011.02291.x.
Gubanova EI, Starovatova PA, Rodina MY. 12-month effects of stabilized HA gel compared with saline for rejuvenation of aging hands. J Drugs Dermatol. 2015;14(3):288–95.
Kablik J, Monheit GD, Yu YL, Chang G, Gershkovich J. Comparative physical properties of hyaluronic acid dermal fillers. Dermatol Surg. 2009;35:302–12. doi:10.1111/j.1524-4725.2008.01046.x.
Kerscher M, Bayrhammer J, Reuther T. Rejuvenating influence of a stabilized HA–based gel of Nonanimal origin on facial skin aging. Dermatol Surg. 2008;34:720–6. doi:10.1111/j.1524-4725.2008.34176.x.
Reuther T, Bayrhammer J, Kerscher M. Effects of a three-session skin rejuvenation treatment using stabilized HA-based gel of non-animal origin on skin elasticity: a pilot study. Arch Dermatol Res. 2010;302:37–45. doi:10.1007/s00403-009-0988-9.
Ribé A, Ribé N. Neck skin rejuvenation: histological and clinical changes after combined therapy with a fractional non-ablative laser and stabilized HA-based gel of non-animal origin. J Cosmet d Laser Ther. 2011;13:154–61.
Streker M, Reuther T, Krueger N, Kerscher M. Stabilized HA-based gel of non- animal origin for skin rejuvenation: face, hand, and Decolletage. J Drugs Dermatol. 2013;12(9):990–4.
Succi IB, DaSilva RT, Orofino-Costa R. Rejuvenation of Periorbital area: treatment with an injectable Nonanimal non-Crosslinked glycerol added HA preparation. Dermatol Surg. 2012;38:192–8. doi:10.1111/j.1524-4725.2011.02182.x.
Talwar HS, Griffiths CE, Fisher GJ, Hamilton TA, Voorhees JJ. Reduced type I and type III procollagens in photodamaged adult human skin. J Invest Dermatol. 1995;105:285–90.
Wang F, Garza LA, Kang S, Varani J, Orringer JS, Fisher GJ, Voorhees JJ. In vivo stimulation of de novo collagen production caused by cross-linked HA dermal filler injections in photodamaged human skin. Arch Dermatol. 2007;143:155–63.
Williams S, Tamburic S, Stensvik H, Weber M. Changes in skin physiology and clinical appearance after microdroplet placement of HA in aging hands. J Cosmet Dermatol. 2009;8:216–25.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this entry
Cite this entry
Ypiranga, S., Fonseca, R. (2017). Hyaluronic Acid for Skinbooster on the Face. In: Issa, M., Tamura, B. (eds) Botulinum Toxins, Fillers and Related Substances. Clinical Approaches and Procedures in Cosmetic Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-20253-2_23-2
Download citation
DOI: https://doi.org/10.1007/978-3-319-20253-2_23-2
Received:
Accepted:
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-20253-2
Online ISBN: 978-3-319-20253-2
eBook Packages: Springer Reference MedicineReference Module Medicine
Publish with us
Chapter history
-
Latest
Hyaluronic Acid for Skin Booster on the Face- Published:
- 08 January 2019
DOI: https://doi.org/10.1007/978-3-319-20253-2_23-3
-
Hyaluronic Acid for Skinbooster on the Face
- Published:
- 01 June 2017
DOI: https://doi.org/10.1007/978-3-319-20253-2_23-2
-
Original
Hyaluronic Acid Filler for Skin Booster on the Face- Published:
- 03 April 2017
DOI: https://doi.org/10.1007/978-3-319-20253-2_23-1