Synonyms
Definition
Preterm birth is defined as babies born alive before the completion of 37 weeks of pregnancy.
Introduction
Preterm birth (PTB) is the leading cause of death in children under five worldwide and its complications are responsible for the deaths of approximately one million children annually. Babies born too soon are predisposed to suffer from neurodevelopmental, respiratory, gastrointestinal, and other complications throughout their lives. Both heritable and environmental risk factors contribute to PTB, and although PTB can be associated with medical disorders such as preeclampsia or intrauterine growth restriction, most cases of PTB occur spontaneously and lack an obvious cause. Ultimately, why spontaneous PTB occurs in humans remains largely a mystery, but important clues can be found in the evolution of the traits and trade-offs that have shaped human pregnancy.
The Burden of Preterm Birth
PTB is a complex,...
References
Abbot, P., & Rokas, A. (2017). Mammalian pregnancy. Current Biology, 27, R127–R128.
Abrams, E. T., & Miller, E. M. (2011). The roles of the immune system in Women’s reproduction: Evolutionary constraints and life history trade-offs. American Journal of Physical Anthropology, 146, 134–154.
Abrams, E. T., & Rutherford, J. N. (2011). Framing postpartum hemorrhage as a consequence of human placental biology: An evolutionary and comparative perspective. American Anthropologist, 113, 417–430.
Adams, M. M., Read, J. A., Rawlings, J. S., Harlass, F. B., Sarno, A. P., & Rhodes, P. H. (1993). Preterm delivery among black and white enlisted women in the United States Army. Obstetrics and Gynecology, 81, 65–71.
Alvergne, A., & Tabor, V. H. (2018). Is female health cyclical? Evolutionary perspectives on menstruation. Trends in Ecology & Evolution, 33, 399–414.
Ashary, N., Tiwari, A., & Modi, D. (2018). Embryo implantation: War in times of love. Endocrinology, 159, 1188–1198.
Babak, T., DeVeale, B., Tsang, E. K., Zhou, Y., Li, X., Smith, K. S., et al. (2015). Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse. Nature, 47, 544–549.
Bainbridge, D. R. (2000). Evolution of mammalian pregnancy in the presence of the maternal immune system. Reviews of Reproduction, 5, 67–74.
Bainbridge, D. R. J. (2014). The evolution of pregnancy. Early Human Development, 90, 741–745.
Barcelona de Mendoza, V., Wright, M. L., Agaba, C., Prescott, L., Desir, A., Crusto, C. A., et al. (2017). A systematic review of DNA methylation and preterm birth in African American women. Biological Research for Nursing, 19, 308–317.
Bezold, K. Y., Karjalainen, M. K., Hallman, M., Teramo, K., & Muglia, L. J. (2013). The genomics of preterm birth: From animal models to human studies. Genome Medicine, 5(4), 34. https://doi.org/10.1186/gm438.
Blackburn, D. G. (2014). Evolution of vertebrate viviparity and specializations for fetal nutrition: A quantitative and qualitative analysis. Journal of Morphology, 276, 961–990.
Blencowe, H., Cousens, S., Chou, D., Oestergaard, M., Say, L., et al. (2013). Born too soon: The global epidemiology of 15 million preterm births. Reproductive Health, 10(Suppl 1), S2. https://doi.org/10.1186/1742-4755-10-S1-S2.
Boardman, J. P. (2008). Preterm birth: Causes, consequences and prevention. Journal of Obstetrics and Gynaecology, 28, 559–559.
Boyd, H. A., Poulsen, G., Wohlfahrt, J., Murray, J. C., Feenstra, B., & Melbye, M. (2009). Maternal contributions to preterm delivery. American Journal of Epidemiology, 170, 1358–1364.
Brown, E. A., Ruvolo, M., & Sabeti, P. C. (2013). Many ways to die, one way to arrive: How selection acts through pregnancy. Trends in Genetics, 29, 585–592.
Brunton, P. J. (2013). Effects of maternal exposure to social stress during pregnancy: Consequences for mother and offspring. Reproduction, 146, R175–R189.
Burton, G. J., & Fowden, A. L. (2015). The placenta: a multifaceted, transient organ. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 370, 20140066–20140066.
Burton, G. J., Fowden, A. L., & Thornburg, K. L. (2016). Placental origins of chronic disease. Physiological Reviews, 96, 1509–1565.
Byrnes, J., Mahoney, R., Quaintance, C., Gould, J. B., Carmichael, S., Shaw, G. M., et al. (2015). Spatial and temporal patterns in preterm birth in the United States. Pediatric Research, 77, 836–844.
Carter, A. M. (2007). Animal models of human placentation – A review. Placenta, 28, S41–S47.
Catalano, R., Gemmill, A., Casey, J., Karasek, D., Stewart, H., & Saxton, K. (2017). Separating the Bruce and Trivers-Willard effects in theory and in human data. American Journal of Human Biology, 30, e23074–e23079.
Catalano, R., Bruckner, T. A., Karasek, D., Yang, W., & Shaw, G. M. (2018). Reproductive suppression, birth defects, and periviable birth. Evolutionary Applications, 11, 762–767.
Christian, L. M., Glaser, R., Porter, K., & Iams, J. D. (2013). Stress-induced inflammatory responses in women. Psychosomatic Medicine, 75, 658–669.
Chu, D. M., Seferovic, M., Pace, R. M., & Aagaard, K. M. (2018). The microbiome in preterm birth. Best Practice & Research. Clinical Obstetrics & Gynaecology (in press). https://doi.org/10.1016/j.bpobgyn.2018.03.006.
Clausson, B., Lichtenstein, P., & Cnattingius, S. (2000). Genetic influence on birthweight and gestational length determined by studies in offspring of twins. BJOG: An International Journal of Obstetrics & Gynaecology, 107, 375–381.
Cobb, C. M., Kelly, P. J., Williams, K. B., Babbar, S., Angolkar, M., & Derman, R. J. (2017). The oral microbiome and adverse pregnancy outcomes. International Journal of Women’s Health, 9, 551–559.
Collins, J. W., David, R. J., Simon, D. M., & Prachand, N. G. (2007). Preterm birth among African American and white women with a lifelong residence in high-income Chicago neighborhoods: An exploratory study. Ethnicity & Disease, 17, 113–117.
Corbett, S., Courtiol, A., Lummaa, V., Moorad, J., & Stearns, S. (2018). The transition to modernity and chronic disease: Mismatch and natural selection. Nature Reviews Genetics, 19, 1–12.
Crespi, B. J. (2010). The origins and evolution of genetic disease risk in modern humans. Annals of the New York Academy of Sciences, 1206, 80–109.
Crespi, E. J., & Denver, R. J. (2004). Ancient origins of human developmental plasticity. American Journal of Human Biology, 17, 44–54.
Crespi, B. J., & Go, M. C. (2015). Diametrical diseases reflect evolutionary-genetic tradeoffs. Evolution, Medicine, and Public Health, 2015, 216–253.
Crespi, B., & Semeniuk, C. (2004). Parent-offspring conflict in the evolution of vertebrate reproductive mode. The American Naturalist, 163, 635–653.
Crump, C., Sundquist, K., Sundquist, J., & Winkleby, M. A. (2011). Gestational age at birth and mortality in young adulthood. JAMA, 306, 1233–1240.
Cyranoski, D. (2018). Gigantic study of Chinese babies yields slew of health data. Nature, 559, 13–14.
De Bonis, M., Torricelli, M., Severi, F. M., Luisi, S., De Leo, V., & Petraglia, F. (2012). Neuroendocrine aspects of placenta and pregnancy. Gynecological Endocrinology, 28, 22–26.
Di Renzo, G. C., Tosto, V., & Giardina, I. (2018). The biological basis and prevention of preterm birth. Best Practice & Research. Clinical Obstetrics & Gynaecology (in press). https://doi.org/10.1016/j.bpobgyn.2018.01.022.
Dunsworth, H., & Eccleston, L. (2015). The evolution of difficult childbirth and helpless hominin infants. Annual Review of Anthropology, 44, 55–69.
Dunsworth, H. M., Warrener, A. G., Deacon, T., Ellison, P. T., & Pontzer, H. (2012). Metabolic hypothesis for human altriciality. Proceedings of the National Academy of Sciences, 109, 15212–15216.
Eidem, H., McGary, K. L., Capra, J. A., Abbot, P., & Rokas, A. (2017). The transformative potential of an integrative approach to pregnancy. Placenta, 57, 204–215.
Forbes, L. S. (1997). The evolutionary biology of spontaneous abortion in humans. Trends in Ecology & Evolution, 12, 446–450.
Frost, J. M., Frost, J. M., & Moore, G. E. (2010). The importance of imprinting in the human placenta. PLoS Genetics, 6, e1001015.
Furness, A. I., Morrison, K. R., Orr, T. J., Arendt, J. D., & Reznick, D. N. (2015). Reproductive mode and the shifting arenas of evolutionary conflict. Annals of the New York Academy of Sciences, 1360, 75–100.
Gluckman, P. D., & Hanson, M. A. (2006). The consequences of being born small – An adaptive perspective. Hormone Research in Paediatrics, 65, 5–14.
Goldenberg, R. L., Culhane, J. F., Iams, J. D., & Romero, R. (2008). Epidemiology and causes of preterm birth. Lancet, 371, 75–84.
Griffith, O. W., Chavan, A. R., Protopapas, S., Maziarz, J., Romero, R., & Wagner, G. P. (2017). Embryo implantation evolved from an ancestral inflammatory attachment reaction. Proceedings of the National Academy of Sciences of the United States of America, 114, E6566–E6575.
Grigsby, P. (2016). Animal models to study placental development and function throughout normal and dysfunctional human pregnancy. Seminars in Reproductive Medicine, 34, 011–016.
Gundling, W. E., & Wildman, D. E. (2015). A review of inter- and intraspecific variation in the eutherian placenta. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 370, 20140072–20140072.
Haig, D. (1993). Genetic conflicts in human pregnancy. The Quarterly Review of Biology, 68, 495–532.
Haig, D. (2008). Intimate relations: Evolutionary conflicts of pregnancy and childhood. In S. C. Stearns & J. C. Koella (Eds.), Evolution in health and disease (pp. 65–76). Oxford: Oxford University Press.
Han, Z., Mulla, S., Beyene, J., Liao, G., & McDonald, S. D. (2010). Maternal underweight and the risk of preterm birth and low birth weight: A systematic review and meta-analyses. International Journal of Epidemiology, 40, 65–101.
Hannibal, R. L., Chuong, E. B., Rivera-Mulia, J. C., Gilbert, D. M., Valouev, A., & Baker, J. C. (2014). Copy number variation is a fundamental aspect of the placental genome. PLoS Genetics, 10, e1004290.
Heap, R. B. (1994). Paracrine and autocrine functions of the placenta: A key to the success of viviparity? Experimental and Clinical Endocrinology, 102, 262–268.
Kistka, Z. A.-F., Palomar, L., Lee, K. A., Boslaugh, S. E., Wangler, M. F., Cole, F. S., et al. (2007). Racial disparity in the frequency of recurrence of preterm birth. American Journal of Obstetrics and Gynecology, 196, 131.e1–131.e6.
Kistka, Z. A.-F., DeFranco, E. A., Ligthart, L., Willemsen, G., Plunkett, J., Muglia, L. J., & Boomsma, D. I. (2008). Heritability of parturition timing: An extended twin design analysis. American Journal of Obstetrics and Gynecology, 199, 43.e1–43.e5.
Macklon, N. S., & Brosens, J. J. (2014). The human endometrium as a sensor of embryo quality. Biology of Reproduction, 91, 179–178.
Martin, R. D. (2008). Evolution of placentation in primates: Implications of mammalian phylogeny. Evolutionary Biology, 35, 125–145.
McLean M, Bisits A, Davies JJ, Woods R, Lowry PJ & Smith R (1995) A placental clock controlling the length of human pregnancy. Nature Medicine, 1, 460–463.
Medawar, P. B. (1953). Some immunological and endocrinological problems raised by the evolution of viviparity in vertebrates. Symposia of the Society for Experimental Biology, 7, 320–338.
Moffett, A., & Loke, Y. W. (2004). The immunological paradox of pregnancy: A reappraisal. Placenta, 25, 1–8.
Monangi, N. K., Brockway, H. M., House, M., Zhang, G., & Muglia, L. J. (2015). The genetics of preterm birth: Progress and promise. Seminars in Perinatology, 39, 574–583.
Monk, D. (2015). Genomic imprinting in the human placenta. American Journal of Obstetrics and Gynecology, 213, S152–S162.
Mor, G., Cardenas, I., Abrahams, V., & Guller, S. (2011). Inflammation and pregnancy: The role of the immune system at the implantation site. Annals of the New York Academy of Sciences, 1221, 80–87.
Muglia, L. J., & Katz, M. (2010). The enigma of spontaneous preterm birth. New England Journal of Medicine, 362, 529–535.
Nelson, D. M. (2015). How the placenta affects your life, from womb to tomb. American Journal of Obstetrics and Gynecology, 213, S12–S13.
Nesse, R. M., Ganten, D., Gregory, T. R., & Omenn, G. S. (2012). Evolutionary molecular medicine. Journal of Molecular Medicine, 90, 509–522.
Norwitz, E. R., Schust, D. J., & Fisher, S. J. (2001). Implantation and the survival of early pregnancy. New England Journal of Medicine, 345, 1400–1408.
Pavličev, M., & Norwitz, E. R. (2017). Human parturition: Nothing more than a delayed menstruation. Reproductive Sciences, 25, 166–173.
Peters, J. (2014). The role of genomic imprinting in biology and disease: An expanding view. Nature Reviews Genetics, 15, 517–530.
Phillips, J. B., Abbot, P., & Rokas, A. (2015). Is preterm birth a human specific syndrome? Evolutionary Medicine and Public Health, 2015, 136–148.
Pike, I. L. (2004). Maternal stress and fetal responses: Evolutionary perspectives on preterm delivery. American Journal of Human Biology, 17, 55–65.
Queller, D. C., & Strassmann, J. E. (2018). Evolutionary conflict. Annual Review of Ecology, Evolution, and Systematics, 49, annurev–ecolsys–110617–062527–21.
Redman, C. W., & Sargent, I. L. (2005). Latest advances in understanding preeclampsia. Science, 308, 1592–1594.
Renfree, M. B., Hore, T. A., Shaw, G., Graves, J. A. M., & Pask, A. J. (2009). Evolution of genomic imprinting: Insights from marsupials and monotremes. Annual Review of Genomics and Human Genetics, 10, 241–262.
Ricklefs, R. E., & Wikelski, M. (2002). The physiology/life-history nexus. Trends in Ecology & Evolution, 17, 462–468.
Roff, D. A., & Fairbairn, D. J. (2007). The evolution of trade-offs: Where are we? Journal of Evolutionary Biology, 20, 433–447.
Romero, R., Gómez, R., Chaiworapongsa, T., Conoscenti, G., Kim, J. C., & Kim, Y. M. (2001). The role of infection in preterm labour and delivery. Paediatric and Perinatal Epidemiology, 15(Suppl 2), 41–56.
Romero, R., Espinoza, J., Kusanovic, J. P., Gotsch, F., Hassan, S., Erez, O., et al. (2006). The preterm parturition syndrome. BJOG: An International Journal of Obstetrics & Gynaecology, 113(Suppl 3), 17–42.
Romero, R., Dey, S. K., & Fisher, S. J. (2014). Preterm labor: One syndrome, many causes. Science, 345, 760–765.
Rosenberg, K., & Trevathan, W. (2002). Birth, obstetrics and human evolution. BJOG: An International Journal of Obstetrics & Gynaecology, 109, 1199–1206.
Say, L., Chou, D., Gemmill, A., Tunçalp, Ö., Moller, A.-B., Daniels, J., et al. (2014). Global causes of maternal death: A WHO systematic analysis. The Lancet. Global Health, 2, e323–e333.
Schlafke, S., & Enders, A. C. (1975). Cellular basis of interaction between trophoblast and uterus at implantation. Biology of Reproduction, 12, 41–65.
Staneva, A., Bogossian, F., Pritchard, M., & Wittkowski, A. (2015). The effects of maternal depression, anxiety, and perceived stress during pregnancy on preterm birth: A systematic review. Women and Birth, 28, 179–193.
Stearns, S. C., & Medzhitov, R. (2015). Evolutionary medicine. Sunderland: Sinauer Associates.
Strauss, J. F., Romero, R., Gomez-Lopez, N., Haymond-Thornburg, H., Modi, B. P., Teves, M. E., et al. (2018). Spontaneous preterm birth: Advances toward the discovery of genetic predisposition. American Journal of Obstetrics and Gynecology, 218, 294–314.e2.
Swaggart, K. A., Pavličev, M., & Muglia, L. J. (2015). Genomics of preterm birth. Cold Spring Harbor Perspectives in Medicine, 5, a023127.
Thornburg, K. L., & Marshall, N. (2015). The placenta is the center of the chronic disease universe. American Journal of Obstetrics and Gynecology, 213, S14–S20.
Treloar, S. A., Macones, G. A., Mitchell, L. E., & Martin, N. G. (2000). Genetic influences on premature parturition in an Australian twin sample. Twin Research, 3, 80–82.
Trevathan, W. (2015). Primate pelvic anatomy and implications for birth. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 370, 20140065–20140065.
Trexler, J. C., & DeAngelis, D. L. (2003). Resource allocation in offspring provisioning: An evaluation of the conditions favoring the evolution of matrotrophy. American Naturalist, 162, 574–585.
Trowsdale, J., & Betz, A. G. (2006). Mother’s little helpers: Mechanisms of maternal-fetal tolerance. Nature Immunology, 7, 241–246.
Urlacher, S. S., Ellison, P. T., Sugiyama, L. S., Pontzer, H., Eick, G., Liebert, M. A., et al. (2018). Tradeoffs between immune function and childhood growth among Amazonian forager-horticulturalists. Proceedings of the National Academy of Sciences of the United States of America, 115, E3914–E3921.
Via, S., & Lande, R. (1985). Genotype-environmental interaction and the evolution of phenotypic plasticity. Evolution, 39, 505–522.
Vogel, J. P., Chawanpaiboon, S., Moller, A.-B., Watananirun, K., Bonet, M., & Lumbiganon, P. (2018). The global epidemiology of preterm birth. Best Practice & Research. Clinical Obstetrics & Gynaecology. https://doi.org/10.1016/j.bpobgyn.2018.04.003.
Wagner, G. P., Kin, K., Muglia, L., & Pavli, M. (2014). Evolution of mammalian pregnancy and the origin of the decidual stromal cell. The International Journal of Developmental Biology, 58, 117–126.
Wells, J. C. K. (2003). The thrifty phenotype hypothesis: Thrifty offspring or thrifty mother? Journal of Theoretical Biology, 221, 143–161.
Wells, J. C. K., DeSilva, J. M., & Stock, J. T. (2012). The obstetric dilemma: An ancient game of Russian roulette, or a variable dilemma sensitive to ecology? American Journal of Physical Anthropology, 149(Suppl 55), 40–71.
Wildman, D. E. (2011). Review: Toward an integrated evolutionary understanding of the mammalian placenta. Placenta, 32, S142–S145.
Wildman, D. E., Chen, C., Erez, O., Grossman, L. I., Goodman, M., & Romero, R. (2006). Evolution of the mammalian placenta revealed by phylogenetic analysis. Proceedings of the National Academy of Sciences of the United States of America, 103, 3203–3208.
Wilkins, J. F., Úbeda, F., & Van Cleve, J. (2016). The evolving landscape of imprinted genes in humans and mice: Conflict among alleles, genes, tissues, and kin. BioEssays, 38, 482–489.
Wolf, J. B., & Hager, R. (2006). A maternal–offspring coadaptation theory for the evolution of genomic imprinting. PLoS Biology, 4, e380.
York, T. P., Eaves, L. J., Neale, M. C., Strauss, J. F., & Strauss, J. F., III. (2014). The contribution of genetic and environmental factors to the duration of pregnancy. American Journal of Obstetrics and Gynecology, 210, 398–405.
Zera, A. J., & Harshman, L. G. (2001). The physiology of life history trade-offs in animals. Annual Review of Ecology and Systematics, 32, 95–126.
Zhang, G., Feenstra, B., Bacelis, J., Liu, X., Muglia, L. M., Juodakis, J., et al. (2017). Genetic associations with gestational duration and spontaneous preterm birth. New England Journal of Medicine, 377, 1156–1167.
Acknowledgments
This research was partially supported by the March of Dimes through the March of Dimes Prematurity Research Center Ohio Collaborative and the Burroughs Wellcome Fund. HRE was supported by a Transdisciplinary Scholar Award from the March of Dimes Prematurity Research Center Ohio Collaborative.
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Abbot, P., Eidem, H.E., Rokas, A. (2018). Preterm Birth. In: Shackelford, T., Weekes-Shackelford, V. (eds) Encyclopedia of Evolutionary Psychological Science. Springer, Cham. https://doi.org/10.1007/978-3-319-16999-6_779-1
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