Definition
Cortisol is a major steroid hormone in humans that is secreted by the adrenal cortex during the experience of stress as part of an adaptive coping response. Cortisol has wide-ranging effects, largely functioning to alter an organism’s immediate response to the stressor, modulate their response to a subsequent stressor, and aid in their adaptation to a chronic stressor.
Introduction
Cortisol is synthesized and secreted by the adrenal cortex following stress-induced activation of the hypothalamic-pituitary-adrenocortical (HPA) axis – the principal endocrine component of the stress response system. During the experience of stress, HPA axis activation causes a neuroendocrine cascade of events that result in the synthesis and secretion of glucocorticoids (GCs) – primarily cortisol in humans and corticosterone in other species. When environments or situations are judged to be harmful, threatening,...
References
Boyce, W. T., & Ellis, B. J. (2005). Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity. Development and Psychopathology, 17, 271–301. doi:10.10170S0954579405050145.
Del Giudice, M., Ellis, B. J., & Shirtcliff, E. A. (2011). The adaptive calibration model of stress responsivity. Neuroscience & Biobehavioral Reviews, 35, 1562–1592. doi:10.1016/j.neubiorev.2010.11.007.
Dickerson, S. S., & Kemeny, M. E. (2004). Acute stressors and cortisol responses: A theoretical integration and synthesis of laboratory research. Psychological Bulletin, 130, 355–391. doi:10.1037/0033–2909.130.3.355.
Gunnar, M. R., & Vazquez, D. (2006). Stress neurobiology and developmental psychopathology. In D. Cicchetti, & D. J. Cohen Developmental Psychopathology (533-577). New Jersey: Wiley. 10.1002/9780470939390.ch13
McEwen, B. S. (1998). Stress, adaptation, and disease: Allostasis and allostatic load. Annals of the New York Academy of Sciences, 840, 33–44. doi:10.1111/j.1749–6632.1998.tb09546.x.
Nesse, R. M., Bhatnagar, S., & Young, E. A. (2010). Evolutionary origins and functions of the. stress response. In G. Fink (Ed.), Encyclopedia of Stress (pp. 965–970). New York: Academic. doi:10.1016/B978-012373947-6.00150-1.
Sapolsky, R. M. (1996). Why stress is bad for your brain. Science, 273, 749–750. doi:141126/science.273.5276.749.
Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000). How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocrine Reviews, 21, 55–89. doi:10.1210/er.21.1.55.
Stroud, L. R., Salovey, P., & Epel, E. S. (2002). Sex differences in stress responses: Social rejection versus achievement stress. Biological Psychiatry, 52, 318–327. doi:191016/S0006–3223(02)01333–1.
Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A., & Updegraff, J. A. (2000). Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight. Psychological Review, 107, 411–429. doi:10.1037/0033-295X.107.3.411.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this entry
Cite this entry
Auer, B.J. (2017). Increased Cortisol. In: Shackelford, T., Weekes-Shackelford, V. (eds) Encyclopedia of Evolutionary Psychological Science. Springer, Cham. https://doi.org/10.1007/978-3-319-16999-6_760-1
Download citation
DOI: https://doi.org/10.1007/978-3-319-16999-6_760-1
Received:
Accepted:
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-16999-6
Online ISBN: 978-3-319-16999-6
eBook Packages: Springer Reference Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences