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Cardiovascular Deconditioning and Exercise

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Abstract

The cardiovascular system in the human body has evolved to support function in the Earth’s gravity environment involving bipedal stance and ambulation. Given that blood and body fluids are drawn downward during standing, autonomic, endocrine, and vascular responses are critical to returning blood from the lower body to the heart and perfuse the brain. Many of these functions are not required during spaceflight, and, in combination with altered blood flow and pressures, results in cardiovascular deconditioning. When not opposed by countermeasures performed during spaceflight to simulate physical work or gravity on Earth, cardiovascular deconditioning can result in low blood volume, cardiac atrophy, vascular dysfunction, orthostatic intolerance, and reduced work capacity, affecting an astronaut’s ability to perform work during and immediately after spaceflight.

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Authors and Affiliations

  1. NASA Johnson Space Center, Houston, TX, USA

    Michael B. Stenger & Steven H. Platts

  2. KBR, Houston, TX, USA

    Steven S. Laurie & Stuart M. C. Lee

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  1. Michael B. Stenger
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  2. Steven S. Laurie
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Correspondence to Michael B. Stenger .

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  1. Massachusetts Institute of Technology, Cambridge, MA, USA

    Laurence R. Young

  2. Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA

    Jeffrey P. Sutton

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  1. Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA

    Peter Norsk

  2. Biomedical Research & Environmental Sciences Division, NASA, Johnson Space Center, Houston, TX, USA

    Peter Norsk

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Stenger, M.B., Laurie, S.S., Lee, S.M.C., Platts, S.H. (2020). Cardiovascular Deconditioning and Exercise. In: Young, L.R., Sutton, J.P. (eds) Handbook of Bioastronautics. Springer, Cham. https://doi.org/10.1007/978-3-319-10152-1_20-2

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    Cardiovascular Deconditioning and Exercise
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    23 October 2020

    DOI: https://doi.org/10.1007/978-3-319-10152-1_20-2

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    Cardiovascular Deconditioning and Exercise
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    DOI: https://doi.org/10.1007/978-3-319-10152-1_20-1

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