Abstract
Pediatric liver transplantation is the standard of care for children with acute liver failure or end-stage liver disease and has excellent outcomes with 5-year survival rates greater than 85%. The most common cause for liver transplantation in children is biliary atresia unlike in adults where end-stage liver disease is most commonly due to nonalcoholic steatohepatitis (NASH). Similarly, intestinal transplantation is offered to those children with intestinal failure who were unable to achieve intestinal rehabilitation or who were born with congenital/inherited diseases such as microvillus inclusion disease. Three-year survival rates with pediatric intestinal transplantation are greater than 65%. The role of the pediatric gastroenterologist/hepatologist is in the early recognition of children who meet the criteria for transplantation and refer them to an appropriate transplantation center for assessment and evaluation. Pediatric gastroenterologists/hepatologists work in a team setting with pediatric surgeons/transplant surgeons, nutritionists, social work, other pediatric providers and nursing to provide children who are awaiting transplantation optimization of their clinical status and to prevent or treat complications associated with end-stage liver disease or intestinal failure which play a critical role in posttransplant outcomes. This chapter focuses on these topics in detail.
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Mansoor, S., Furuya, K.N. (2018). Pediatric Gastroenterologist and the Infant and Child Before Liver and Small Bowel Transplantation. In: Dunn, S., Horslen, S. (eds) Solid Organ Transplantation in Infants and Children. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-08049-9_76-2
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DOI: https://doi.org/10.1007/978-3-319-08049-9_76-2
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Pediatric Gastroenterologist and the Infant and Child Before Liver and Small Bowel Transplantation- Published:
- 15 February 2018
DOI: https://doi.org/10.1007/978-3-319-08049-9_76-2
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Pediatric Gastroenterologist and the Infant and Child Before Liver and Small Bowel Transplantation- Published:
- 17 October 2017
DOI: https://doi.org/10.1007/978-3-319-08049-9_76-1