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Positive Inotropic Activity (Cardiac Glycosides)

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Drug Discovery and Evaluation: Pharmacological Assays

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Abstract

Biological standardization of cardiac glycosides was necessary as long as the drugs used in therapy were plant extracts or mixtures of various glycosides. They were standardized in units of an international standard. Some of the pharmacological methods used for these purposes and adopted by many pharmacopoeias have nowadays historical interest only. This holds true for the frog method and the pigeon method (Burn et al. 1950).

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References and Further Reading

General Considerations

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  1. CorDynamics, Inc., 2242 W. Harrison St., Suite 108, 60612, Chicago, IL, USA

    Michael Gralinski, Liomar A. A. Neves & Olga Tiniakova

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  1. Michael Gralinski
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  2. Liomar A. A. Neves
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  3. Olga Tiniakova
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Correspondence to Michael Gralinski .

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  1. CorDynamics, Dieburg, Germany

    Franz J. Hock

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Gralinski, M., Neves, L.A.A., Tiniakova, O. (2016). Positive Inotropic Activity (Cardiac Glycosides). In: Hock, F. (eds) Drug Discovery and Evaluation: Pharmacological Assays. Springer, Cham. https://doi.org/10.1007/978-3-319-05392-9_9

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