Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Cardiovascular Activity

    1. Front Matter
      Pages 1-1
    2. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 3-39
    3. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 41-133
    4. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 135-164
    5. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 165-216
    6. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 217-236
    7. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 237-286
    8. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 287-333
    9. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 335-347
    10. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 349-428
    11. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 429-472
    12. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 473-496
    13. Liomar A. A. Neves, Olga Tiniakova
      Pages 497-511
    14. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 513-553
    15. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 555-566
    16. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 567-586
    17. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 587-610
    18. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 611-644
    19. Michael Gralinski, Liomar A. A. Neves, Olga Tiniakova
      Pages 645-663

About this book

Introduction

The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc.

Keywords

assays drug action drugs pharmacological tests toxicology

Editors and affiliations

  • Franz J. Hock
    • 1
  1. 1.CorDynamicsDieburgGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-05392-9
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-05391-2
  • Online ISBN 978-3-319-05392-9
  • About this book
Industry Sectors
Biotechnology
Consumer Packaged Goods
Pharma