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Effects on Behavior and Muscle Coordination

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Drug Discovery and Evaluation: Pharmacological Assays

Abstract

The effects of drugs on the central and peripheral nervous systems can be easily recognized in normal animals. This does not necessarily mean that these effects can be used in therapy. Observing the global effects of drugs during LD50 determinations, pharmacologists can detect psychotropic activity. Only if these effects occur also in doses considerably below the LD50 are further evaluations justified. This basic experience resulted in the development of a variety of observational tests and activity measurements.

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References and Further Reading

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    Mary Jeanne Kallman

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    Franz J. Hock

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Kallman, M.J. (2016). Effects on Behavior and Muscle Coordination. In: Hock, F. (eds) Drug Discovery and Evaluation: Pharmacological Assays. Springer, Cham. https://doi.org/10.1007/978-3-319-05392-9_26

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