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NO Activity and Rho Kinase Activity

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Drug Discovery and Evaluation: Pharmacological Assays

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Abstract

The endothelium releases a labile, diffusible, vasorelaxing substance that has been termed endothelium-derived relaxing factor (EDRF) (Furchgott and Zawadzki 1980). Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor (Palmer et al. 1987; Vanhoutte 1999).

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  1. CorDynamics, Inc., 2242 W. Harrison St., Suite 108, Chicago, IL, 60612, USA

    Michael Gralinski, Liomar A. A. Neves & Olga Tiniakova

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  1. Michael Gralinski
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  2. Liomar A. A. Neves
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  3. Olga Tiniakova
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Correspondence to Michael Gralinski .

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  1. CorDynamics, Dieburg, Germany

    Franz J. Hock

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Gralinski, M., Neves, L.A.A., Tiniakova, O. (2016). NO Activity and Rho Kinase Activity. In: Hock, F. (eds) Drug Discovery and Evaluation: Pharmacological Assays. Springer, Cham. https://doi.org/10.1007/978-3-319-05392-9_143

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