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In Vivo or Ex Vivo Models of Thromobis

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Drug Discovery and Evaluation: Pharmacological Assays

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Abstract

In vitro model systems are limited in assessing the impact of global or systemic factors that propagate coagulation and/or platelet activation. Clinically relevant model systems of thrombosis are crucial in assessing the impact of both local (vascular endothelium, atherosclerosis, and other local factors) and systemic factors responsible for coagulation and platelet activation.

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References and Further Reading

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  1. The Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, 1 Discovery Drive, Albany, NY, 12144, USA

    Shaker A. Mousa

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    Franz J. Hock

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Mousa, S.A. (2016). In Vivo or Ex Vivo Models of Thromobis. In: Hock, F. (eds) Drug Discovery and Evaluation: Pharmacological Assays. Springer, Cham. https://doi.org/10.1007/978-3-319-05392-9_13

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