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Local Field Potential, Relationship to Membrane Synaptic Potentials

Encyclopedia of Computational Neuroscience

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Definition

The relationship between the somatic membrane potential of an individual neuron and the local field potential signals, assessed by cross-correlation, coherence, or related statistical analysis methods. Typically, correlation between these two signals exists due to synaptic inputs shared by the individual neuron and the entire neuronal population.

Detailed Description

Introduction

The membrane potential (Vm) of neurons is shaped by transmembrane flow of ions, which can have both synaptic and intrinsic origins. A net flow of current across the membrane, in addition to the change in Vm, produces a small change in the potential of the extracellular medium outside the cell that can be picked up by an extracellular microelectrode. The low-frequency (<300 Hz) component of this signal, known as the extracellular local field potential (LFP), is produced by transmembrane currents flowing simultaneously in thousands of neuron and glial cells, superimposed according to the complex...

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Author information

Authors and Affiliations

  1. Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel

    Dr. Aryeh H. Taub & Ilan Lampl

  2. Institute of Neurology, University College London, London, UK

    Michael Okun

Authors
  1. Dr. Aryeh H. Taub
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  2. Ilan Lampl
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  3. Michael Okun
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Corresponding author

Correspondence to Aryeh H. Taub .

Editor information

Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Taub, A.H., Lampl, I., Okun, M. (2014). Local Field Potential, Relationship to Membrane Synaptic Potentials. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_728-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_728-1

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  • Online ISBN: 978-1-4614-7320-6

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Chapter history

  1. Latest

    Local Field Potential: Relationship to Membrane Synaptic Potentials
    Published:
    18 June 2019

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_728-2

  2. Original

    Local Field Potential, Relationship to Membrane Synaptic Potentials
    Published:
    14 March 2014

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_728-1

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