Encyclopedia of Computational Neuroscience

Living Edition
| Editors: Dieter Jaeger, Ranu Jung

Wireless Microstimulators

Living reference work entry

Latest version View entry history

DOI: https://doi.org/10.1007/978-1-4614-7320-6_605-3

Synonyms

Definition

Electrical currents for neural stimulation have conventionally been delivered via metal wires to the electrode that is in contact with the tissue. The wire connections attached to these rigid electrodes, floating in a very soft medium like neural tissue, not only damage the surrounding cells from tethering forces but also limit the longevity of the implant due to wire breakage in chronic implants. Wireless transfer of stimulus energy as well as the pulse parameters to a floating electrode or an array of electrodes has gained interest in recent years as a method to eliminate the associated problems with tethering wires. Considering the properties of the neural tissue, different types of energy transfer mechanisms have been proposed for energizing the implant wirelessly: electromagnetic radio-frequency (RF), optical, and acoustic waves. The implanted electrode(s) may or may not have active electronics for storing the...

Keywords

Permeability Titanium Microwave Attenuation Platinum 
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References

  1. Abdo A, Sahin M (2011) Feasibility of neural stimulation with floating-light-activated microelectrical stimulators. IEEE Trans Biomed Circuits Syst 5:179–188CrossRefGoogle Scholar
  2. Abdo A, Ersen A, Sahin M (2011a) Temperature elevation inside neural tissue illuminated by NIR laser. Eng Med Biol Soc EMBC Annu Int Conf IEEE 2011:3987–3989Google Scholar
  3. Abdo A, Sahin M, Freedman DS, Cevik E, Spuhler PS, Unlu MS (2011b) Floating light-activated microelectrical stimulators tested in the rat spinal cord. J Neural Eng 8:056012PubMedCentralPubMedCrossRefGoogle Scholar
  4. Abdo A, Ersen A, Sahin M (2013) Near-infrared light penetration profile in the rodent brain. J Biomed Opt 18:075001PubMedCrossRefGoogle Scholar
  5. Center for Devices and Radiological Health (2008) Information for manufacturers seeking marketing clearance of diagnostic ultrasound systems and transducers. United states department of health and human services, food and drug administration, MarylandGoogle Scholar
  6. Cogan SF (2008) Neural stimulation and recording electrodes. Annu Rev Biomed Eng 10:275–309PubMedCrossRefGoogle Scholar
  7. Freedman DS, Spuhler PS, Cevik E, Unlu MS, Sahin M (2011) Addressable floating light activated micro-electrical stimulators for wireless neurostimulation. Neural Eng NER Int IEEE/EMBS Conf 2011:486–489CrossRefGoogle Scholar
  8. Gulick DW, Towe BC (2012) Method of locating ultrasound-powered nerve stimulators. Eng Med Biol Soc EMBC Annu Int Conf IEEE 2012:887–890Google Scholar
  9. Heetderks WJ (1988) RF powering of millimeter-and submillimeter-sized neural prosthetic implants. Biomed Eng IEEE Trans 35:323–327CrossRefGoogle Scholar
  10. Kane MJ, Breen PP, Quondamatteo F, ÓLaighin G (2011) BION microstimulators: a case study in the engineering of an electronic implantable medical device. Med Eng Phys 33:7–16PubMedCrossRefGoogle Scholar
  11. Kiyatkin EA (2004) Brain hyperthermia during physiological and pathological conditions: causes, mechanisms, and functional implications. Curr Neurovasc Res 1:77–90PubMedCrossRefGoogle Scholar
  12. Loeb GE, Peck RA, Moore WH, Hood K (2001) BIONTM system for distributed neural prosthetic interfaces. Med Eng Phys 23:9–18PubMedCrossRefGoogle Scholar
  13. Ozeri S, Shmilovitz D (2010) Ultrasonic transcutaneous energy transfer for powering implanted devices. Ultrasonics 50:556–566PubMedCrossRefGoogle Scholar
  14. Poon ASY, O’Driscoll S, Meng TH (2010) Optimal frequency for wireless power transmission into dispersive tissue. IEEE Trans Antennas Propag 58:1739–1750CrossRefGoogle Scholar
  15. Rabaey JM, Mark M, Chen D, Sutardja C, Tang C, Gowda S, Wagner M, Werthimer D (2011) Powering and communicating with mm-size implants. Des Autom Test Eur Conf Exhib DATE 2011:1–6Google Scholar
  16. Sahin M, Pikov V (2011) Wireless microstimulators for neural prosthetics. Crit Rev Biomed Eng 39:63–77PubMedCrossRefGoogle Scholar
  17. Schulman JH (2008) The feasible FES system: battery powered BION stimulator. Proc IEEE 96:1226–1239CrossRefGoogle Scholar
  18. Song Y-K, Stein J, Patterson WR, Bull CW, Davitt KM, Serruya MD, Zhang J, Nurmikko AV, Donoghue JP (2007) A microscale photovoltaic neurostimulator for fiber optic delivery of functional electrical stimulation. J Neural Eng 4:213–218PubMedCrossRefGoogle Scholar
  19. Towe BC, Larson PJ, Gulick DW (2009) Wireless ultrasound-powered biotelemetry for implants. Eng Med Biol Soc EMBC Annu Int Conf IEEE 2009:5421–5424Google Scholar
  20. Towe BC, Larson PJ, Gulick DW (2012) A microwave powered injectable neural stimulator. Eng Med Biol Soc EMBC Annu Int Conf IEEE 2012:5006–5009Google Scholar
  21. Wells PNT (1977) Biomedical ultrasonics. Academic Press, New YorkGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • David S. Freedman
    • 1
  • Mesut Sahin
    • 2
  • Bruce C. Towe
    • 3
  1. 1.Department of Electrical and Computer EngineeringBoston UniversityBostonUSA
  2. 2.Biomedical Engineering, New Jersey Institute of TechnologyUniversity HeightsNewarkUSA
  3. 3.School of Biological and Health Systems EngineeringArizona State UniversityTempeUSA