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Local Field Potential, Relationship to Unit Activity

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Encyclopedia of Computational Neuroscience

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Synonyms

Contamination by spikes; Electroencephalogram; Local field potential; Relation to unit activity; Spike contribution; Spike-triggered average

Definition

Unit activity usually refers to timing of spikes elicited by individual neurons (single unit activity, SUA) or local (r < 140 μm) population of neurons (multi-unit activity, MUA; Buzsáki 2004). Although local field potential (LFP) reflects both subthreshold and spiking activities that are summed over larger population of neurons (r < 450 μm, Berens et al. 2008), usually it does not display discriminable spikes. Nevertheless, the amplitude of high-frequency LFP (>40 Hz) often correlates with population firing rate, whereas the phase and amplitude of low-frequency LFP (<10 Hz) modulates this relationship. The LFP-spike relation is very sensitive to neuronal correlations – at high synchrony levels neurons produce macroscopic spikes visible in the raw LFP signal (“population spikes”).

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Author information

Authors and Affiliations

  1. Unit of Neuroscience, Information and Complexity (UNIC), Centre National de la Recherche Scientifique (CNRC), Gif-sur-Yvette, France

    Bartosz Telenczuk

  2. Paris Saclay University, CNRS, Neuro-PSI, Gif sur Yvette, France

    Bartosz Telenczuk & Alain Destexhe

Authors
  1. Bartosz Telenczuk
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  2. Alain Destexhe
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Corresponding author

Correspondence to Bartosz Telenczuk .

Editor information

Editors and Affiliations

  1. Atlanta, GA, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, FL, USA

    Ranu Jung

Section Editor information

  1. Paris-Saclay University, Institute of Neuroscience (NeuroPSI), CNRS, Gif sur Yvette, France

    Alain Destexhe

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Telenczuk, B., Destexhe, A. (2020). Local Field Potential, Relationship to Unit Activity. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_543-2

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_543-2

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  • Print ISBN: 978-1-4614-7320-6

  • Online ISBN: 978-1-4614-7320-6

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Chapter history

  1. Latest

    Local Field Potential, Relationship to Unit Activity
    Published:
    10 November 2020

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_543-2

  2. Original

    Local Field Potential, Relationship to Unit Activity
    Published:
    13 March 2014

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_543-1

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