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Comparative Analysis of Half-Center Central Pattern Generators (CPGs)

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Encyclopedia of Computational Neuroscience

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Definition

CPGs are networks of neurons that can produce rhythmic activity, featuring a stereotyped sequence of phases that repeats in a periodic-like manner, without receiving rhythmic inputs from an outside source. Half-center CPGs, also known as half-center oscillators, are CPGs consisting of two components connected by reciprocal synaptic inhibition. While the coupled network exhibits a two-phase pattern, with one component exhibiting a high activity level and the other at a low activity level in each phase, the individual components are not able to switch between sustained high and low activity phases in isolation. Comparative analysis of half-center CPGs is the study of how specific features of half-center CPGs translate into particular properties.

Detailed Description

A half-center CPG consists of a pair of components and the coupling between them. Each component may be an individual neuron or a population of neurons. In a half-center oscillation, each component switches back...

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References

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Author information

Authors and Affiliations

  1. Department of Mathematics, University of Pittsburgh, Pittsburgh, PA, USA

    Jonathan E. Rubin

Authors
  1. Jonathan E. Rubin
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Correspondence to Jonathan E. Rubin .

Editor information

Editors and Affiliations

  1. Atlanta, GA, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, FL, USA

    Ranu Jung

Section Editor information

  1. Department of Neurobiology and Anatomy, Drexel University, College of Medicine, Philadelphia, PA, USA

    Jessica Ausborn

  2. Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, USA

    Ilya Rybak

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Rubin, J.E. (2019). Comparative Analysis of Half-Center Central Pattern Generators (CPGs). In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_39-2

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_39-2

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-7320-6

  • Online ISBN: 978-1-4614-7320-6

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Chapter history

  1. Latest

    Comparative Analysis of Half-Center Central Pattern Generators (CPGs)
    Published:
    25 September 2019

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_39-2

  2. Original

    Comparative Analysis of Half-Center Central Pattern Generators (CPGs)
    Published:
    06 February 2014

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_39-1

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