Encyclopedia of Computational Neuroscience

Living Edition
| Editors: Dieter Jaeger, Ranu Jung

Connectome, Drosophila

  • Arjun BhariokeEmail author
  • Louis K. Scheffer
  • Dmitri B. Chklovskii
  • Ian A. Meinertzhagen
Living reference work entry

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DOI: https://doi.org/10.1007/978-1-4614-7320-6_275-2

Definition

The Drosophila connectome is a comprehensive description of all the connections between subunits comprising the central nervous system (CNS) of the fruit fly, Drosophila melanogaster.

The CNS of Drosophila consists of the brain and ventral ganglion. It has a volume of ~0.07 mm 3 (see Rein et al. 2002, Table 1). To compare, this is similar to the volume of a single cortical column in mouse barrel cortex (~0.09 mm 3) (Lefort et al. 2009; Hooks et al. 2011). The Drosophila brain can be subdivided into smaller neuropil compartments (Fig. 1), identified through anatomical boundaries (Ito et al. 2014), as well as the overlapping arborizations of the neurons constituting each neuropil compartment (Chiang et al. 2011; Jenett et al. 2012). In total, across these compartments, the Drosophilabrain is thought to contain ~90,000 cells, of which ~90% are neurons. These neurons can be classified into discrete cell types, with stereotypical shapes and synaptic connections, using both human...
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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Arjun Bharioke
    • 1
    Email author
  • Louis K. Scheffer
    • 1
  • Dmitri B. Chklovskii
    • 1
  • Ian A. Meinertzhagen
    • 2
  1. 1.Janelia Farm Research CampusHoward Hughes Medical InstituteAshburnUSA
  2. 2.Department of Psychology and NeuroscienceDalhousie UniversityHalifaxCanada

Section editors and affiliations

  • David Mayerich
    • 1
  1. 1.Department of Electrical and Computer EngineeringUniversity of HoustonHoustonUSA