Living reference work entry
The Drosophila connectome is a comprehensive description of all the connections between subunits comprising the central nervous system (CNS) of the fruit fly, Drosophila melanogaster.
The CNS of Drosophila consists of the brain and ventral ganglion. It has a volume of ~0.07 mm 3 (see Rein et al. 2002, Table 1). To compare, this is similar to the volume of a single cortical column in mouse barrel cortex (~0.09 mm 3) (Lefort et al. 2009; Hooks et al. 2011). The Drosophila brain can be subdivided into smaller neuropil compartments (Fig. 1), identified through anatomical boundaries (Ito et al. 2014), as well as the overlapping arborizations of the neurons constituting each neuropil compartment (Chiang et al. 2011; Jenett et al. 2012). In total, across these compartments, the Drosophilabrain is thought to contain ~90,000 cells, of which ~90% are neurons. These neurons can be classified into discrete cell types, with stereotypical shapes and synaptic connections, using both human...
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