Electrical Biosensors: Peripheral Nerve Sensors

  • Clemens Eder
  • Andreas Demosthenous
Living reference work entry


The chapter provides an overview of techniques for sensing activity from peripheral nerves. It describes the measurement chain from the origin of the signal source and the acquisition of signals from electrodes to their amplification. Discussion of the concepts of interfacing with biological systems is explained from the concept of the electronic engineer. The biological signals are in some cases stochastic and difficult to extract with often unexpected and poorly defined differential mode interference sources, which degrade the signals. Tissue and electrode impedances behave quite differently from simple lumped components and depend on many factors. Additionally, precautions have to be taken to ensure the safety of the body in which the electronics are implanted. This chapter provides an introductory background and tools for implementing a measurement chain for peripheral nerve sensing, helping the reader to acquire an appreciation of the design challenges.


Constant Phase Element Bias Current Recording Electrode Compound Action Potential Electrode Impedance 
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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of Electronic & Electrical EngineeringUniversity College LondonLondonUK

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