Definition
The process of gaining information about a metagenomic community from sequence data using a variety of interdisciplinary techniques and approaches.
Introduction
The history of computational approaches to metagenomic data analysis is brief given the rapid development of the field. In 1998, a visionary paper described techniques for investigation of the molecular diversity of environmental communities and coined the term metagenome (Handelsman et al. 1998). Focus was placed on screening clone libraries for interesting biological activities, a mainly laboratory-based endeavor which has been continually successful at identifying relevant novel genes with novel functionality. Other researchers took a more technology-driven approach by randomly sequencing metagenomic DNA from an acid mine biofilm and the well-known Sargasso Sea projects. These sequence-based approaches required considerable computational capacity for...
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Chouvarine, P., Tümmler, B., Davenport, C. (2015). Computational Approaches for Metagenomic Datasets. In: Nelson, K. (eds) Encyclopedia of Metagenomics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6418-1_739-2
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DOI: https://doi.org/10.1007/978-1-4614-6418-1_739-2
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Latest
Computational Approaches for Metagenomic Datasets- Published:
- 27 May 2015
DOI: https://doi.org/10.1007/978-1-4614-6418-1_739-2
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Original
Computational Approaches for Metagenomic Datasets- Published:
- 04 April 2014
DOI: https://doi.org/10.1007/978-1-4614-6418-1_739-1