Abstract
Phosphorylation is a posttranslational modification used to regulate the functions of a variety of proteins, including neurotransmitter receptors. Protein phosphorylation is catalyzed by protein kinases transferring a phosphate molecule from ATP to a protein substrate. The addition of the negatively charged phosphate group alters the structure of the protein and regulates its functional properties. Protein phosphorylation is a highly regulated reversible process and thus the level of receptor phosphorylation in neurons is constantly modified by neurotransmitters and other cellular signals released by surrounding neurons.
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Wang (2003). Study of Opioid Receptor Phosphorylation Using Cell-Labeling Method with 32P-Orthrophosphate. In: Pan, Z.Z. (eds) Opioid Research. Methods in Molecular Biology™, vol 84. Humana Press. https://doi.org/10.1385/1-59259-379-8:47
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DOI: https://doi.org/10.1385/1-59259-379-8:47
Publisher Name: Humana Press
Print ISBN: 978-1-58829-059-5
Online ISBN: 978-1-59259-379-8
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