Abstract
Determining the subcellular location of molecular motors is an essential step in understanding their function and regulation. Although much attention has been focused on the ability of kinesin-like motors to bind reversibly to microtubules, the interaction of this family with cargo has not been extensively studied. Thus, the interactions of kinesin with membrane-bound organelles (MBOs) remains poorly understood, although kinesins are widely thought to serve as motors for movement of MBOs (see also Chapter 12). Methods presented in this chapter were developed to study the regulation of the membrane association of kinesins.
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References
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Morfini, G., Tsai, MY., Szebenyi, G., Brady, S.T. (2001). Approaches to Study Interactions Between Kinesin Motors and Membranes. In: Vernos, I. (eds) Kinesin Protocols. Methods in Molecular Biology™, vol 164. Humana Press. https://doi.org/10.1385/1-59259-069-1:147
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DOI: https://doi.org/10.1385/1-59259-069-1:147
Publisher Name: Humana Press
Print ISBN: 978-0-89603-766-3
Online ISBN: 978-1-59259-069-8
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