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Isolation of Large Gel-Forming Mucins

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Glycoprotein Methods and Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 125))

Abstract

The large gel-forming mucins, which form the major macromolecular components of mucous secretions, are members of the mucin “superfamily.” Nine mucin genes (MUC1-MUC4, MUC5AC, MUC5B, and MUC6-MUC8) have been identified (for reviews see refs. 1 and 2, with each gene showing expression in several tissues. Only the MUC1, MUC2, MUC4, MUC5, and MUC7 mucins have been sequenced completely (311) although large stretches of MUC5AC (1215) as well as the C-terminal sequences of MUC3 (16) and MUC6 (17) are now known.

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© 2000 Humana Press Inc.

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Davies, J.R., Carlstedt, I. (2000). Isolation of Large Gel-Forming Mucins. In: Corfield, A.P. (eds) Glycoprotein Methods and Protocols. Methods in Molecular Biology™, vol 125. Humana Press. https://doi.org/10.1385/1-59259-048-9:003

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  • DOI: https://doi.org/10.1385/1-59259-048-9:003

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-720-5

  • Online ISBN: 978-1-59259-048-3

  • eBook Packages: Springer Protocols

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