Abstract
The human immunodeficiency viruses type 1 and 2 (HIV-1, HIV-2) are members of the lentivirus subfamily of the retroviruses. As typical for all retroviruses, viral RNA replication requires the synthesis of a DNA intermediate, which is stably integrated into the host cell DNA (termed provirus). HIV can induce, after a long clinically silent period, the acquired immune deficiency syndrome (AIDS). In the case of HIV-1 infections, the majority of individuals will finally suffer from this late disease; whereas HIV-2 infections appear to exhibit a lower frequency of progression to AIDS.
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© 1996 Humana Press Inc.
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Böni, J. (1996). PCR Detection of HIV. In: Clapp, J.P. (eds) Species Diagnostics Protocols. Methods in Molecular Biology™, vol 50. Humana Press. https://doi.org/10.1385/0-89603-323-6:93
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DOI: https://doi.org/10.1385/0-89603-323-6:93
Publisher Name: Humana Press
Print ISBN: 978-0-89603-323-8
Online ISBN: 978-1-59259-537-2
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