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An Immunochemical Assay for Detecting Transition of B-DNA to Z-DNA

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Immunochemical Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 10))

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Abstract

The enzyme immunoassay technique described below is a simple and sensitive method to detect left-handed Z-DNA formation in synthetic polynucleotides, recombinant plasmids, and native DNAs. This method utilizes the differences in the antigenic properties of right-handed B-DNA and left-handed Z-DNA.

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Author information

Authors and Affiliations

  1. Department of Medicine, Division of Rheumatology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, Canada

    T. J. Thomas

Authors
  1. T. J. Thomas
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Editor information

Editors and Affiliations

  1. Medical Research Council Laboratories, Carshalton, Surrey, UK

    Margaret M. Manson

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© 1992 The Humana Press, Inc., Totowa, NJ

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Thomas, T.J. (1992). An Immunochemical Assay for Detecting Transition of B-DNA to Z-DNA. In: Manson, M.M. (eds) Immunochemical Protocols. Methods in Molecular Biology, vol 10. Humana Press, Totowa, NJ. https://doi.org/10.1385/0-89603-204-3:337

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  • DOI: https://doi.org/10.1385/0-89603-204-3:337

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-0-89603-204-0

  • Online ISBN: 978-1-59259-497-9

  • eBook Packages: Springer Protocols

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