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Production of Monoclonal Antibodies for the Detection of Chemically Modified DNA

  • Protocol
Immunochemical Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 10))

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Abstract

Monoclonal antibodies that are specific for sites of base modification in DNA have a number of applications in, for example, studies of carcinogenesis, drug action, or DNA repair (1). The production of antibodies of the appropriate specificity entails practical considerations that are specific to this type of antigen.

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Author information

Authors and Affiliations

  1. Leukaemia Research Fund Unit, Newcastle University, Newcastle-upon-Tyne, UK

    Michael J. Tilby

Authors
  1. Michael J. Tilby
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Editor information

Editors and Affiliations

  1. Medical Research Council Laboratories, Carshalton, Surrey, UK

    Margaret M. Manson

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© 1992 The Humana Press, Inc., Totowa, NJ

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Tilby, M.J. (1992). Production of Monoclonal Antibodies for the Detection of Chemically Modified DNA. In: Manson, M.M. (eds) Immunochemical Protocols. Methods in Molecular Biology, vol 10. Humana Press, Totowa, NJ. https://doi.org/10.1385/0-89603-204-3:321

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  • DOI: https://doi.org/10.1385/0-89603-204-3:321

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-0-89603-204-0

  • Online ISBN: 978-1-59259-497-9

  • eBook Packages: Springer Protocols

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