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Electrophysiological Assessment of Spinal Cord Function on Rodents Using tcMMEP and SSEP

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Animal Models of Acute Neurological Injuries II

Part of the book series: Springer Protocols Handbooks ((SPH))

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Abstract

Electrophysiological assays following experimental spinal cord injury objectively evaluate neurological function in the rodent. Major descending and ascending tracts can be monitored noninvasively using motor-evoked potentials and somatosensory-evoked potentials, respectively. This chapter summarizes the methods, procedures, and materials used to carry out these tests in our laboratory. Interpretation of results is also discussed.

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Authors and Affiliations

  1. Norton Neuroscience Institute, Louisville, KY, USA

    Yi Ping Zhang, Lisa B. E. Shields & Christopher B. Shields

Authors
  1. Yi Ping Zhang
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  2. Lisa B. E. Shields
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  3. Christopher B. Shields
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Corresponding author

Correspondence to Christopher B. Shields .

Editor information

Editors and Affiliations

  1. School of Medicine, University of Pittsburgh, Terrace St. 3500, Pittsburgh, 15213, Pennsylvania, USA

    Jun Chen

  2. School of Medicine, Stark Neurosciences Res. Inst., Indiana University, W. Walnut St. 950, Indianapolis, 46202, Indiana, USA

    Xiao-Ming Xu

  3. School of Medicine, Department of Anatomy & Cell Biology, Indiana University, Barnhill Dr. 635, Indianapolis, 46202, Indiana, USA

    Zao C. Xu

  4. School of Medicine, Dept. Neurosurgery, Loma Linda University, Anderson St. 11234, Loma Linda, 92354, California, USA

    John H. Zhang

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Zhang, Y.P., Shields, L.B.E., Shields, C.B. (2012). Electrophysiological Assessment of Spinal Cord Function on Rodents Using tcMMEP and SSEP. In: Chen, J., Xu, XM., Xu, Z., Zhang, J. (eds) Animal Models of Acute Neurological Injuries II. Springer Protocols Handbooks. Humana Press. https://doi.org/10.1007/978-1-61779-782-8_43

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  • DOI: https://doi.org/10.1007/978-1-61779-782-8_43

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-781-1

  • Online ISBN: 978-1-61779-782-8

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