Animal Models of Acute Neurological Injuries II

Injury and Mechanistic Assessments, Volume 2

  • Jun Chen
  • Xiao-Ming Xu
  • Zao C. Xu
  • John H. Zhang

Part of the Springer Protocols Handbooks book series (SPH)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. R. Anne Stetler, Miguel A. Perez-Pinzon
    Pages 1-3
  3. Global Cerebral Ischemia

  4. Focal Cerebral Ischemia

    1. Front Matter
      Pages 91-91
    2. Feng Zhang, Steven H. Graham, Jun Chen
      Pages 107-114
    3. Xiaoming Hu, Jun Chen
      Pages 139-148
    4. Feng-Yan Sun, Xiao Sun, Ji-Jiang Wang, Qiu-Wan Zhang, Yong-Quan Wang
      Pages 163-179

About this book


The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries.  Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system.  Volume 2 examines global cerebral ischemia, focal cerebral ischemia, and neonatal hypoxia-ischemia, as well as intensive sections covering traumatic brain injury and spinal cord injury.  Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used.


Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.


Acute neurological injury Animal models Focal cerebral ischemia Global cerebral ischemia Neonatal Hypoxia-Ischemia Spinal cord injury Traumatic brain injury

Editors and affiliations

  • Jun Chen
    • 1
  • Xiao-Ming Xu
    • 2
  • Zao C. Xu
    • 3
  • John H. Zhang
    • 4
  1. 1.School of MedicineUniversity of PittsburghPittsburghUSA
  2. 2.School of Medicine, Stark Neurosciences Res. Inst.Indiana UniversityIndianapolisUSA
  3. 3.School of Medicine, Department of Anatomy & Cell BiologyIndiana UniversityIndianapolisUSA
  4. 4.School of Medicine, Dept. NeurosurgeryLoma Linda UniversityLoma LindaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-781-1
  • Online ISBN 978-1-61779-782-8
  • Series Print ISSN 1949-2448
  • Series Online ISSN 1949-2456
  • About this book
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